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2.A.3.3.5 The brain L-cationic (Arg, Lys, Orn, 2,4-diamino-n-butyrate) transporter, CAT3 (capacity of trans-stimulation by internal Arg) (Ito and Groudine, 1997)
Accession Number:	P70423
Protein Name:	Cationic amino acid transporter 3 aka CAT3
Length:	618
Molecular Weight:	67460.00
Species:	Mus musculus (Mouse) [10090]
Number of TMSs:	15
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate	lysine, ornithine, arginine

RefSeq:	NP_031541.1
Entrez Gene ID:	11989
Pfam:	PF00324
KEGG:	mmu:11989
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0055085 P:transmembrane transport
References (4) [1] “A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.” Ito K.et.al. 9334265 [2] “The transcriptional landscape of the mammalian genome.” Carninci P.et.al. 16141072 [3] “Lineage-specific biology revealed by a finished genome assembly of the mouse.” Church D.M.et.al. 19468303 [4] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MLWQALRRFG QKLVRRRVLE LGMGETRLAR CLSTLDLVAL GVGSTLGAGV YVLAGEVAKD 
61:	KAGPSIVICF LVAALSSVLA GLCYAEFGAR VPGSGSAYLY SYVTVGELWA FTTGWNLILS 
121:	YVIGTASVAR AWSSAFDNLI GNHISRTLKG TILLKMPHVL AEYPDFFALA LVLLLTGLLV 
181:	LGASKSALVT KVFTGMNLLV LSFVIISGFI KGELRNWKLT KEDYCLTMSE SNGTCSLDSM 
241:	GSGGFMPFGL EGILRGAATC FYAFVGFDCI ATTGEEAQNP QRSIPMGIVI SMFICFLAYF 
301:	GVSSALTLMM PYYKLHPESP LPEAFSYVGW EPARYLVAIG SLCALSTSLL GSMFPMPRVM 
361:	YSMAEDGLLF RVLAKVHSVT HIPIVATLVS GVIAAFMAFL FELTDLVDLM SIGTLLAHSL 
421:	VSICVLILRY QPDQEMKSVE EEMELQEETL EAEKLTVQAL FCPVNSIPTL LSGRVVYVCS 
481:	SLLAVLLTVL CLVLTWWTTP LRSGDPVWVT VVVLILGLIL AISGVIWRQP QNRTPLHFKV 
541:	PAVPLLPLVS IFVNVYLMMQ MTAGTWARFG IWMLIGFAIY FGYGIQHSMK EVKNHQTLPK 
601:	TRAQTIDLDL TTSCVHSI

2.A.3.3.5
The brain L-cationic (Arg, Lys, Orn, 2,4-diamino-n-butyrate) transporter, CAT3 (capacity of trans-stimulation by internal Arg) (Ito and Groudine, 1997)

Cross database links:

Gene Ontology

References (4)

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Analyze:

2.A.3.3.5The brain L-cationic (Arg, Lys, Orn, 2,4-diamino-n-butyrate) transporter, CAT3 (capacity of trans-stimulation by internal Arg) (Ito and Groudine, 1997)

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

2.A.3.3.5
The brain L-cationic (Arg, Lys, Orn, 2,4-diamino-n-butyrate) transporter, CAT3 (capacity of trans-stimulation by internal Arg) (Ito and Groudine, 1997)