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| Accession Number: | Q50E62 |
| Protein Name: | Aromatic-preferring amino acid transporter |
| Length: | 488 |
| Molecular Weight: | 53100.00 |
| Species: | Mus musculus (Mouse) [10090] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Virion membrane1 / Single-pass type III membrane protein2 |
| Substrate | L-dopa, alanine, serine, cystine, arginine, phenylalanine, histidine, tryptophan, tyrosine, glutamic acid |
Cross database links:
| RefSeq: | NP_001033749.1 |
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| Entrez Gene ID: | 328059 |
| Pfam: | PF00324 |
| KEGG: | mmu:328059 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0043234
C:protein complex
GO:0015171
F:amino acid transmembrane transporter activity
GO:0046982
F:protein heterodimerization activity
GO:0006865
P:amino acid transport
GO:0055085
P:transmembrane transport
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References (2)[1] “Identification and functional characterization of a novel low affinity aromatic-preferring amino acid transporter (arpAT). One of the few proteins silenced during primate evolution.” Fernandez E.et.al. 15757906 [2] “A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.” Mural R.J.et.al. 12040188
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MERSEEKDGS NKPAGQEQGS GTAGLMLKRE IGLWSAVSMT AGCMIGSGIF MSPQGVLVYI 61: GSPGASLIVW ATCGLLAMLG ALCYAELGSL VPESGGDYAY ILRTFGSLPA FLVIYVYVLV 121: GRPAGITAVS LSFAEYVLAP FYPGCSSLPQ VIVKIVASSC ILLLLLINFW SSRMSTVLMN 181: VCTTAKVFSL LVIVVGGAVV LMQGHASTES LLFAFHNTTQ QAGRIGMAFY QGLWSFDGWS 241: NINTVIEELK NPKQNLLWAV MTAVPLVTIL YVLVNISYLL VMSPSEILSS DAIAVIWGDR 301: VLGSWAWLVP LAVALSTFGT VNGGFFSGSR VCYAAAREGH MPQLMSMIHV NRLTPAPAQI 361: FTTAVALLLV IPGNFSTFVN LLSFLSWLTY GTTFACLLYL RIKTKNLPHT YKVPTFIPAI 421: MLLVSLYLVL APIIDHPQIE FLYIFLFVLS GFPVYFLLFH FQCQFKCIQT ATMHLQLLLE 481: VAPTTKDH