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2.A.3.9.1
Spore germination protein A2 (AB) (amino acid [L-alanine] receptor.) GerAA, GerAB and GerAC form a receptor complex in the spore inner membrane. GerAC is a lipoprotein (Cooper and Moir, 2011). GerAB is an α-helical transmembrane protein containing a water channel. Alanine binds transiently to specific sites on GerAB, initiating L-alanine-mediated signaling by GerAB, which facilitates early events in spore germination (Blinker et al. 2021).

Accession Number:P07869
Protein Name:GRAB aka GERAB aka GERA2
Length:365
Molecular Weight:41459.00
Species:Bacillus subtilis [1423]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate L-alanine

Cross database links:

RefSeq: NP_391186.1   
Entrez Gene ID: 935948   
Pfam: PF03845   
KEGG: bsu:BSU33060   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006865 P:amino acid transport
GO:0009847 P:spore germination

References (4)

[1] “The nucleotide sequence and gene organization of the gerA spore germination operon of Bacillus subtilis 168.”  Zuberi A.R.et.al.   3110007
[2] “The yvsA-yvqA (293 degrees - 289 degrees) region of the Bacillus subtilis chromosome containing genes involved in metal ion uptake and a putative sigma factor.”  Wipat A.et.al.   9639930
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[4] “Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria.”  Reizer J.et.al.   8382989

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MSQKQTPLKL NTFQGISIVA NTMLGAGLLT LPRALTTKAN TPDGWITLIL EGFIFIFFIY 
61:	LNTLIQKKHQ YPSLFEYLKE GLGKWIGSII GLLICGYFLG VASFETRAMA EMVKFFLLER 
121:	TPIQVIILTF ICCGIYLMVG GLSDVSRLFP FYLTVTIIIL LIVFGISFKI FDINNLRPVL 
181:	GEGLGPIANS LTVVSISFLG MEVMLFLPEH MKKKKYTFRY ASLGFLIPII LYILTYIIVV 
241:	GALTAPEVKT LIWPTISLFQ SFELKGIFIE RFESFLLVVW IIQFFTTFVI YGYFAANGLK 
301:	KTFGLSTKTS MVIIGITVFY FSLWPDDANQ VMMYSDYLGY IFVSLFLLPF ILFFIVALKR 
361:	RITTK