2.A.30.1.10
The Na+/K+Cl- cotransporter, NKCC1 of 1036 aas and 11 or 12 TMSs. In several insects, it is involved in prostaglandin E2-promoted immune responses. PGE2 mediates oenocytoid cell lysis (a class of lepidopteran hemocytes: OCL) via a specific membrane
receptor to release inactive prophenoloxidase (PPO) into the hemolymph (Shrestha et al. 2015).
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| Accession Number: | H9IW41 |
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| Protein Name: | Uncharacterized protein |
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| Length: | 1036 |
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| Molecular Weight: | 114164.00 |
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| Species: | Bombyx mori (Silk moth) [7091] |
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| Number of TMSs: | 11 |
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| Substrate |
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1: MEDNRFVVST VEGECKKNGI HMGANIISRP LRSSLETVER GVTNAQPDTW LHDAGWRRKR
61: SLAQLTREAL PRMENYRNSK RALKRPSLGE LHGDHLITEE GVLIPCLLNI WGVMLFLRIS
121: WVVSQAGIGW SLVIIALSAV VCVITTLSMS AICTNGEVKG GGIYYIISRS LGPEFGASVG
181: IIFAFANAVA ASMNTIGFCD SMNHLLKSLD LQIIDNSYND VRIIGAIALF VMCVICAVGM
241: DWESKAQNFL IAIIVGAIVD FVVGAVMGPK SNLEVAEGFV GLSTSTFVEN FNSDFKYSEG
301: MEQNFFSVFA IFFPSVTGIQ AGANISGDLK DPASAIPKGT LLALLISMVS YAMMVLFTGA
361: AALRDASGNI TDLVISNGTV TNYSAVSQCA NSTLFPCKYG MHVDFEIMQL MSAWGPFIYA
421: GCWAATLSTA LTNLLSVPRL IQALGVDRIY PGLIFFSKPY GRHGEAYRGY VLTFLVSLLF
481: LLIAKLNAIA PLISNFYLAS YALINFCTFH AALVRPLGWR PTFKYYNVWV SLAGFLMCVG
541: IMLLISWIMS LVTIAIFFTL YLIVHYRNPD VNWGSSTQAQ MYKTALSSAH NLARTGEHVK
601: NYWPQLLVLG GRAHARPPLV DLGSLITKAG SLMIIGDISK EKLSYKVCSA RARADNEWLQ
661: ERKVRAFCSL VHGFNFEQGA RALIQATGVG KLAPNVLLMG YKSDWTTASA EDLVAYFNVL
721: HTAFENRLAV AIVRVRGGLD YGAAGGGEEG AGSLTVTSSG SGELHVRRSD ALIMHADSDL
781: DIHTDSSAKN NLSNILTLST SRSFTITDAK DIKDKKKKDK RPTDMHRQII YNAANGIELS
841: KDQLTQMSIF KRKQESGTVD VWWLYDDVGL TILLPYIISQ RSAWGNCKLR IFALANRLNE
901: MELEERNMAN LLSKFRIDYS SLTMVQDITE PPQAETKALF DETIKKFTSD SAAPECRISE
961: TELTTLSGKT NRQLRLRELL LANSRDSRLI VMSLPMPRKG SVSAPLYMAW LEMMSRDLPP
1021: MLFVRGNHTS VLTFYS