2.A.30.1.19
K+,Cl--cotransporter, KCC or Slc12a5b of 1117 aas and 12 TMSs. Ion transport via an ortholog is oxygen-sensitive and is regulated by two different oxygen sensors in crucian carp (Carassius carassius) (Berenbrink et al. 2006).
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| Accession Number: | E9QC71 |
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| Protein Name: | Solute carrier family 12 (potassium/chloride transporter), member 5b |
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| Length: | 1117 |
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| Molecular Weight: | 123156.00 |
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| Species: | Danio rerio (Zebrafish) [7955] |
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| Number of TMSs: | 11 |
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| Substrate |
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1: MMNNLNECEE GDGGPNSQGD ATSKESSPFI NSSTSDVEKS QQYDGKNMAL FEEEMDTSPM
61: VSSLLSSLAN YSNLTQGSKE HEEAENNEEA RKKAAQAPRM GTIMGVYLPC LQNILGVILF
121: LRMTWLVGVG GVLGTFTIVF MCCSTTMLTA ISMSAIATNG VVPAGGSYYM ISRSLGPEFG
181: GAVGICFFLG TTFAGAMYIL GCIEILLIYI VPSAAIFKME GLEGSEAEAA LLNNMRVYGT
241: IVLTFMAIVV FVGVKYVNKL ALVFLACVIL SILAIYAGVI KTSFDPPDFP VCVLGNRTLV
301: SKAYDICAKT IERGNATITT KLWRSFCDSE FLNATCDEYF VNNNISQIQG IPGVTSGILA
361: ENLFSGYMEK NSVLEKRGLQ AVQDPELPVT NSNRYVLADI TSFFTLLVGI YFPSVTGIMA
421: GSNRSGDLQD AQKSIPVGTI LAITTTSIIY MSSVILFGAC VDGVVLRDKF GEGVSGNLVI
481: GTLAWPSPWV IVFGSFFSTC GAGLQSLTGA PRLLQAIARD GIIPFLRVFG HGKANGEPTW
541: ALLLTACICE SGILIASLDA VAPILSMFFL MCYMFVNLAC ALQTLLRTPN WRPRFKFYHW
601: ALSLLGMSLC LTLMFLCSWY YAIVAMVIAG CIYKYIEFCG AEKEWGDGIR GISLSAARFA
661: LMRLEEGPPH TKNWRPQILV LTTLDGEQNV EQPRLLSLTS QLKAGKGLTI VGACIEGTYL
721: NNQPKTQKAD QSLRKLMEVE KVKGFSQVVI SSNLRDATSH LIQAGGLGGL RHNTVLVSFP
781: KNWKQAEEHH RCRNFIEVVR ETTAGHMALL VPKNISAYPS NGERFTEGHI DVWWIVHDGG
841: MLMLLPFLLR QHKVWRKCKM RIFTVAQMDD NSIQMKKDLM TFLYHLRLDA AVEVVEMLDN
901: DISAYTYEKT LMMEQRSQIL KEMHLTKNER EREIQSITDV SRGSIRRKNP SNLHPQRSIA
961: EESVAGSGEE KPEEEVQLIQ GKNATPTPTS PTSPTAPTPA TMSPGEEIQM TWTDDTEKAN
1021: NPAVANPENI KDMFNMKPEW ENLNQSNVRR MHHAQKLNEV IVKKSQEAKL VLLNMPGPPR
1081: NRTGEENYME FLEVLTEGLN RVLLVRGGGR EVITIYS