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| Accession Number: | O07553 |
| Protein Name: | Na(+)/H(+) antiporter NhaC |
| Length: | 453 |
| Molecular Weight: | 48053.00 |
| Species: | Bacillus subtilis (strain 168) [224308] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), hydron |
Cross database links:
| Entrez Gene ID: | 936274 |
|---|---|
| Pfam: | PF03553 |
| KEGG: | bsu:BSU09680 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015297
F:antiporter activity
GO:0006814
P:sodium ion transport
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References (5)[1] “The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus subtilis chromosome contains several dysfunctional genes, the glyB marker, many genes encoding transporter proteins, and the ubiquitous hit gene.” Noback M.A.et.al. 9579061 [2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F.et.al. 9384377 [3] “Two types of Bacillus subtilis tetA(L) deletion strains reveal the physiological importance of TetA(L) in K(+) acquisition as well as in Na(+), alkali, and tetracycline resistance.” Wang W.et.al. 10735849 [4] “Bacillus subtilis YqkI is a novel malic/Na+-lactate antiporter that enhances growth on malate at low protonmotive force.” Wei Y.et.al. 10903309 [5] “Bacillus subtilis NhaC, an Na+/H+ antiporter, influences expression of the phoPR operon and production of alkaline phosphatases.” Pragai Z.et.al. 11274110
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MDSQKKLTFP LAVGLFIFML CIIISCLFLL HVEPHIPLFL SVVMLSAAAL WFGFPWKSIE 61: KGIVDGIKNG VQPIIVLALI GILIGAWMYS GAIPTMTVYA LSFIEPSHLL LTALFSCMII 121: STLVGSSLTT VSTIGVALIG VASAAGVPLE WTAGAVICGA CFGDKMSPMS DTTNFAAGIG 181: EIPIFEHIRH MMGTTIPALL ITVVLFYFLG SSVSADAAST DNIQQVITGI KDAANVTPWA 241: LLSPLLVVLL AMKRVSVIPV LTAGIISSGI LTAIFVPYSS LQAFMTALQN GTTFETDNEA 301: AAKIINRGGL QSMMGSVSLI MIAFALGGLM EKIGLISALL EGVMKGIRSK GRLVAATVCS 361: SIGVNLATGE QYLSILIPGQ SFKSLYDKRN IQRKFLTRSL EDGGTLINPL IPWGVSGAFM 421: ASALGVPVID YIPFTFFLYI SPMISILIGF VKK