2.A.36.6.11
Na+/H+ antiporter, NhaP2 (YcgO; CvrA) of 578 aas and 13 TMSs. Involved in growth at low osmolarity, intracellular K+ maintenance, and volume regulation (Verkhovskaya et al. 2001).
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| Accession Number: | P76007 |
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| Protein Name: | K(+)/H(+) antiporter NhaP2 |
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| Length: | 578 |
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| Molecular Weight: | 62285.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 13 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
sodium(1+) |
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1: MDATTIISLF ILGSILVTSS ILLSSFSSRL GIPILVIFLA IGMLAGVDGV GGIPFDNYPF
61: AYMVSNLALA IILLDGGMRT QASSFRVALG PALSLATLGV LITSGLTGMM AAWLFNLDLI
121: EGLLIGAIVG STDAAAVFSL LGGKGLNERV GSTLEIESGS NDPMAVFLTI TLIAMIQHHE
181: SNISWMFIVD ILQQFGLGIV IGLGGGYLLL QMINRIALPA GLYPLLALSG GILIFSLTTA
241: LEGSGILAVY LCGFLLGNRP IRNRYGILQN FDGLAWLAQI AMFLVLGLLV NPSDLLPIAI
301: PALILSAWMI FFARPLSVFA GLLPFRGFNL RERVFISWVG LRGAVPIILA VFPMMAGLEN
361: ARLFFNVAFF VVLVSLLLQG TSLSWAAKKA KVVVPPVGRP VSRVGLDIHP ENPWEQFVYQ
421: LSADKWCVGA ALRDLHMPKE TRIAALFRDN QLLHPTGSTR LREGDVLCVI GRERDLPALG
481: KLFSQSPPVA LDQRFFGDFI LEASAKYADV ALIYGLEDGR EYRDKQQTLG EIVQQLLGAA
541: PVVGDQVEFA GMIWTVAEKE DNEVLKIGVR VAEEEAES