2.A.37.2.5
Na+/H+ exchanger of 732 aas. The exchanger is the N-terminal domain, and the C-terminal domain is in the cl00292 superfamily of adenine nucleotide alpha hydrolases. This superfamily
includes N-type ATP PPases, ATP sulphurylases, Universal Stress Response
proteins and electron transfer flavoproteins (ETF). The domain forms a
apha/beta/apha fold which binds to adenosine nucleotides.
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| Accession Number: | B3EE21 |
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| Protein Name: | Sodium/hydrogen exchanger |
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| Length: | 732 |
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| Molecular Weight: | 80179.00 |
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| Species: | Chlorobium limicola (strain DSM 245 / NBRC 103803) [290315] |
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| Number of TMSs: | 13 |
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| Substrate |
sodium(1+), hydron |
|---|
1: MFLNGLTEIT LPLKNPVLQF SLILFIILFV PFFLKRLRIP SLISLIIAGA VAGPHGLNLM
61: LRDSSIILFG TVGLLYIMFL AGLEIDVADF KKNSGKSILF GLYTFLISQL LGFFVALYVL
121: GFSLLSSVLI GSIFASHTLI VYPVVSRLGI AKDKAVNIAV GGTMITDTLA LLVLAVVAGS
181: SSGELTSAFW IRLFIGITIF SLIVLLLFPF IARWFFKRFD DSVLQYLFVL GMVFFAAFLA
241: EVAGVEAIIG AFLGGLSLNR LIPHTSALMN RIRFAGDAIF IPFFLIGVGM LIDFRAFFKD
301: AETIKVALVI TVAATVAKYF SAWITQKIYG FSVDQRRLIF GLISAHAAVA LATVLIGYNS
361: ITGYTLDGDP VRLLDKSVLN GTILFILVTC TLASIVGEKG AQNIAFAELA DEASSPDVHA
421: APERILIPMN DMKTVDELVN LGITIKSPKN RDGLFALHVA DSTSPGGAVE KHAEKLLEKA
481: VITAASTDND LTGVFRYDTS VANGIAGVAR EQRVTDIILG LHHKSSLADS FLGGLSEMLL
541: ATCNGTIFIY KPVQPLATIK RTIAVIPEGA ESEEGFIFWK DRLSNMVNNS SSKLIFYASK
601: QTLGYLKEYH SASFPNAEYK IFRTLDEFSG LAKEVRSDDN IVVVMSRRNY RSWHSRMAKI
661: PAYLGKYFGR NSFILIYPVQ SGGADESIAF SESRLSGGIQ FSMVPLRSQV ESMLKRVSFK
721: RISLRRNRKE PQ