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2.A.38.3.1
High affinity K+ transporter, Hkt1 (K+:Na+ symporter) (Kato et al., 2007). The ortholog in Populus trichocarpa enhances salt tolerance and improves the efficiency of antioxidant systems, suggesting that PeHKT1;1 plays an important role in response to salt stress (Xu et al. 2018). Similarly, the barley orthologs in Hordeum vulgaris and the halophilic H. maritimum are K+:Na+ sympoorters, but the ortholog of the halophyte, H. maritium (93% identical to the wheat homologue), has higher affinity for both cations, and plays a role in adaptation to high salenity (Hmidi et al. 2019).

Accession Number:Q41515
Protein Name:Hkt1
Length:533
Molecular Weight:58917.00
Species:Triticum aestivum (Wheat) [4565]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Endosome membrane1 / Multi-pass membrane protein2
Substrate sodium(1+), potassium(1+)

Cross database links:

Pfam: PF02386   
BioCyc: MetaCyc:MONOMER-14576   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0015079 F:potassium ion transmembrane transporter act...
GO:0006813 P:potassium ion transport
GO:0055085 P:transmembrane transport

References (1)

[1] “Structure and transport mechanism of a high-affinity potassium uptake transporter from higher plants.”  Schachtman D.P.et.al.   8065452

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MGRVKRFYQD FIHIKLHSFC RISGYVVDSI AFVYRFVALH VHPFWIQLSY FLAIAILGSV 
61:	LLMSLKPSNP DFSPPYIDML FLSTSALTVS GLSTITMEDL SSSQIVVLTL LMLIGGEIFV 
121:	SLLGLMLRVN HQDMQDLPSV KISSVPVELE ELDLPNSMAL CDESQLEEAA HAIPPKKCTE 
181:	LKRSRSVKCL GYVVFGYFAM IHVLGFLLVF LYITHVPTAS APLNKKGINI VLFSLSVTVA 
241:	SCANAGLVPT NENMVIFSKN SGLLLLLSGQ MLAGNTLFPL FLRLLVWFLG RITKVKELRL 
301:	MINNPEEVRF ANLLARLPTV FLSSTVVGLV AAGVTMFCAV DWNSSVFDGL SSYQKTVNAF 
361:	FMVVNARHSG ENSIDCSLMS PAIIVLFIVM MYLPSSATFA PPSGDTKTTN ENTKGKVKRG 
421:	SLVQNLAFSP LGCNIIFVMV ACITERRRLR NDPLNFSTLN MIFEVISAYG NAGLSTGYSC 
481:	SRLHQLHPEI ICQDKPYSFS GWWSDGGKFV LILVMLYGRL KAFTLATGKS WKV