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2.A.40.7.1 The purine (hypoxanthine/adenine/guanine) transporter, AzgA (Cecchetto et al., 2004). Topological modeling has revealed a potential substrate binding cavity, and residues important for transport activity have been identified (Krypotou et al. 2014).
Accession Number:	Q7Z8R3
Protein Name:	AzgA
Length:	580
Molecular Weight:	62089.00
Species:	Emericella nidulans (Aspergillus nidulans) [162425]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate	adenine, guanine, hypoxanthine

RefSeq:	XP_681803.1
Entrez Gene ID:	2868800
Pfam:	PF00860
KEGG:	ani:AN8534.2
Gene Ontology GO:0016020 C:membrane GO:0005215 F:transporter activity GO:0055085 P:transmembrane transport
References (2) [1] “The AzgA Purine Transporter of Aspergillus nidulans (subtitle: characterization of a protein belonging to a new phylogenetic cluster).” Cecchetto G.et.al. 14597637 [2] “Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.” Galagan J.E.et.al. 16372000

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MGYAEWIGRT NAAVARSPVG RWFRLEGSGH PRERKGAYFF TELRAGLATF FAMAYIISVN 
61:	ANITSDTGGT CVCPAEDLAT ACDNNTEYLL CKQEVNRDLV TATAAIAAIA SFFLGLLANL 
121:	PVALAPGMGL NAYFAYTVVG HHGTGLIPYS LAVTAVFVEG WIFLGLTLLG IRQWLARAIP 
181:	ASIKLATGAG IGLYLTLIGL SYSAGLGVVQ GGTSSPIQLA GCASDTFGDD GLCPSSEKMR 
241:	NPTMWIGIFC GGVFTVFLMM YRVKGAVIAG ILLVSIISWP RPTPVTYFPH TETGDSSFDF 
301:	FKKVVTFHPI QHTLVAQEWN ISSNGGQFGL ALITFLYVDI LDATGTLYSM AKFAGAMDER 
361:	TQDFEGSAMA YMVDAICISI GSLFGSPPVT AFVESGAGIS EGGKTGLTSC MTGICFFIAV 
421:	FFAPIFASIP PWATGSTLVI VGSMMMHATL EINWRYLGDA VPAFLTISLM PFTYSIADGL 
481:	IAGILSYILI NGGVWIVAKL TGGRISPPNR EEEHEPWTWK IPGGFFPPWL VRAVHGKKDF 
541:	WRAEDDANDL SLGVMPHGSL SSQDRAGEKL ASSKEQVTEK

2.A.40.7.1
The purine (hypoxanthine/adenine/guanine) transporter, AzgA (Cecchetto et al., 2004). Topological modeling has revealed a potential substrate binding cavity, and residues important for transport activity have been identified (Krypotou et al. 2014).

Cross database links:

Gene Ontology

References (2)

External Searches:

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2.A.40.7.1The purine (hypoxanthine/adenine/guanine) transporter, AzgA (Cecchetto et al., 2004). Topological modeling has revealed a potential substrate binding cavity, and residues important for transport activity have been identified (Krypotou et al. 2014).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

2.A.40.7.1
The purine (hypoxanthine/adenine/guanine) transporter, AzgA (Cecchetto et al., 2004). Topological modeling has revealed a potential substrate binding cavity, and residues important for transport activity have been identified (Krypotou et al. 2014).