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| Accession Number: | O34987 |
| Protein Name: | BACSU Hypoxanthine/guanine permease aka PbuG |
| Length: | 440 |
| Molecular Weight: | 46191.00 |
| Species: | Bacillus subtilis [1423] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | guanosine, hypoxanthine |
Cross database links:
| RefSeq: | NP_388518.1 |
|---|---|
| Entrez Gene ID: | 936043 |
| Pfam: | PF00860 |
| BioCyc: | SUBTI:BSU06370-MONOMER |
| KEGG: | bsu:BSU06370 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005215
F:transporter activity
GO:0055085
P:transmembrane transport
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References (5)[1] “The 52 degrees-55 degrees segment of the Bacillus subtilis chromosome: a region devoted to purine uptake and metabolism, and containing the genes cotA, gabP and guaA and the pur gene cluster within a 34960 bp nucleotide sequence.” Borriss R.et.al. 8969499 [2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F.et.al. 9384377 [3] “Genetic and physiological characterization of Bacillus subtilis mutants resistant to purine analogs.” Saxild H.H.et.al. 3110131 [4] “Definition of the Bacillus subtilis PurR operator using genetic and bioinformatic tools and expansion of the PurR regulon with glyA, guaC, pbuG, xpt-pbuX, yqhZ-folD, and pbuO.” Saxild H.H.et.al. 11591660 [5] “Definition of a second Bacillus subtilis pur regulon comprising the pur and xpt-pbuX operons plus pbuG, nupG (yxjA), and pbuE (ydhL).” Johansen L.E.et.al. 12923093
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKTFFQFDEL GTSYRNEIIG GLTTFLSMAY ILFVNPITLA LESVKDFPEA LRIDQGAVFT 61: ATALASAAGC ILMGLIARYP IAIAPGMGLN AFFAFSVVLG MGISWQAALS GVFISGLIFV 121: ALSLTGFREK IINAIPPELK LAVGAGIGLF ITFVGLQGSG IITANPSTLV TIGNIHSGPV 181: LLTIFGVIVT VILMVLRVNA GVFIGMLLTA VAGMIFGLVP VPTQIIGSVP SLAPTFGQAW 241: IHLPDIFSVQ MLIVILTFLF VGFFDTAGTL VAVATQAGLM KENKLPRAGR ALLADSSSIV 301: IGAVLGTSTT TSYVESSSGV AAGARSGFAA IVTGILFLLA TFFSPLLSVV TSNVTAPALI 361: IVGALMVAPL GKIAWDKFEV AVPAFLTMIM MPLTYSIATG IAIGFIFYPI TMVCKGKAKE 421: VHPIMYGLFV VFILYFIFLK