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| Accession Number: | Q62773 |
| Protein Name: | CNT2 aka SPNT |
| Length: | 659 |
| Molecular Weight: | 72615.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 13 |
| Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
| Substrate | sodium(1+), 7H-purine |
Cross database links:
| RefSeq: | NP_113852.1 |
|---|---|
| Entrez Gene ID: | 60423 |
| Pfam: | PF07670 PF07662 PF01773 |
| KEGG: | rno:60423 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0001882
F:nucleoside binding
GO:0005415
F:nucleoside:sodium symporter activity
GO:0006810
P:transport
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References (3)[1] “Primary structure and functional expression of a cDNA encoding the bile canalicular, purine-specific Na(+)-nucleoside cotransporter.” Che M.et.al. 7775409 [2] “Transport of adenosine by recombinant purine- and pyrimidine-selective sodium/nucleoside cotransporters from rat jejunum expressed in Xenopus laevis oocytes.” Yao S.Y.et.al. 8967974 [3] “A nucleoside transporter is functionally linked to ectonucleotidases in rat liver canalicular membrane.” Che M.et.al. 1315767
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MAKSEGRKSA SQDTSENGME NPGLELMEVG NLEQGKTLEE VTQGHSLKDG LGHSSLWRRI 61: LQPFTKARSF YQRHAGLFKK ILLGLLCLAY AAYLLAACIL NFRRALALFV ITCLVIFILA 121: CHFLKKFFAK KSIRCLKPLK NTRLRLWLKR VFMGAAVVGL ILWLALDTAQ RPEQLISFAG 181: ICMFILILFA CSKHHSAVSW RTVFWGLGLQ FVFGILVIRT EPGFNAFQWL GDQIQIFLAY 241: TVEGSSFVFG DTLVQSVFAF QSLPIIIFFG CVMSILYYLG LVQWVIQKIA WFLQITMGTT 301: AAETLAVAGN IFVGMTEAPL LIRPYLADMT LSEIHAVMTG GFATIAGTVL GAFISFGIDA 361: SSLISASVMA APCALALSKL VYPEVEESKF KSKEGVKLPR GEERNILEAA SNGATDAIAL 421: VANVAANLIA FLAVLAFINS TLSWLGEMVD IHGLTFQVIC SYVLRPMVFM MGVQWADCPL 481: VAEIVGVKFF INEFVAYQQL SQYKNKRLSG VEEWINGEKQ WISVKAEIIA TFSLCGFANL 541: TSIGITLGGL TSMVPQRKSD LCKLVVRALF TGACVSFISA CMAGILYVPR GAETDCVSFL 601: NTNFTNRTYE TYVCCRELFQ STLLNGTNMP SFSGPWQDKE SSLRNLAKCC DLYTSTVCA