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2.A.47.1.6 The tonoplast dicarboxylate (malate) transporter, AtDCT (Kovermann et al., 2007). The ortholog (70% identity) in tomatos increases the malate while decreasing the citrate concentrations, influencing flavor (Liu et al. 2017).
Accession Number:	Q8LG88
Protein Name:	Tonoplast dicarboxylate transporter
Length:	540
Molecular Weight:	58098.00
Species:	[3702]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Vacuole membrane¹ / Multi-pass membrane protein²
Substrate	citrate salt, malate(2-)

RefSeq:	NP_199567.1
Entrez Gene ID:	834806
Pfam:	PF00939
KEGG:	ath:AT5G47560
Gene Ontology GO:0016021 C:integral to membrane GO:0005774 C:vacuolar membrane GO:0015140 F:malate transmembrane transporter activity GO:0015743 P:malate transport GO:0051453 P:regulation of intracellular pH GO:0006814 P:sodium ion transport GO:0055085 P:transmembrane transport
References (3) [1] “The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier.” Emmerlich V.et.al. 12947042 [2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.” Yamada K.et.al. 14593172 [3] “Impaired pH homeostasis in Arabidopsis lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast.” Hurth M.A.et.al. 15728336

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MNGGDVTVAG SDDLKSPLLP VVHNDEPFER QTVGQQLRTI FTPKNCYIAL GPLLCAVVCL 
61:	CVDLGGDETT TARNMLGVLV WMFAWWLTEA VPMPITSMTP LFLFPLFGIS AADDVANSYM 
121:	DDVISLVLGS FILALAVEHY NIHRRLALNI TLVFCVEPLN APLLLLGICA TTAFVSMWMH 
181:	NVAAAVMMMP VATGILQRLP SSSSTTEVVH PAVGKFSRAV VLGVIYSAAV GGMSTLTGTG 
241:	VNLILVGMWK SYFPEADPIS FSQWFFFGFP LALCIFVVLW CVLCVMYCPK GAGQALSPYL 
301:	HKSHLRRELD LLGPMNFAEK MVLAVFGGLV VLWMTRNITD DIPGWGRIFA GRAGDGTVSV 
361:	MMATLLFIIP SNIKKGEKLM DWNKCKKLPW NIVLLLGAGF AIADGVRTSG LAEVLSKGLV 
421:	FLETAPYWAI APTVCLIAAT ITEFTSNNAT TTLLVPLLIE IAKNMGIHPL LLMVPGAIGA 
481:	QFAFLLPTGT PSNVVGFTTG HIEIKDMIKT GLPLKIAGTI FLSILMPTLG AYVFASMGGV

2.A.47.1.6
The tonoplast dicarboxylate (malate) transporter, AtDCT (Kovermann et al., 2007). The ortholog (70% identity) in tomatos increases the malate while decreasing the citrate concentrations, influencing flavor (Liu et al. 2017).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.47.1.6The tonoplast dicarboxylate (malate) transporter, AtDCT (Kovermann et al., 2007). The ortholog (70% identity) in tomatos increases the malate while decreasing the citrate concentrations, influencing flavor (Liu et al. 2017).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

2.A.47.1.6
The tonoplast dicarboxylate (malate) transporter, AtDCT (Kovermann et al., 2007). The ortholog (70% identity) in tomatos increases the malate while decreasing the citrate concentrations, influencing flavor (Liu et al. 2017).