TCDB » SEARCH

« See all members of the family

2.A.47.3.3 L-tartrate:succinate antiporter, TtdT (YgjE). (also takes up meso and L-tartrate and succinate; does not transport D-tartrate) (Kim and Unden, 2007). It is induced in the presence of L- or meso tartrate under anaerobic conditions in the presence of TtdR (Kim et al. 2009).
Accession Number:	P39414
Protein Name:	TTDT aka YgiE aka YGJE aka B3063
Length:	487
Molecular Weight:	52906.00
Species:	Escherichia coli [83333]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	eliglustat tartrate, succinate(2-)

RefSeq:	AP_003613.1 NP_417535.1
Entrez Gene ID:	947576
Pfam:	PF00939
BioCyc:	EcoCyc:YGJE-MONOMER ECOL168927:B3063-MONOMER
KEGG:	ecj:JW3035 eco:b3063
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015297 F:antiporter activity GO:0006814 P:sodium ion transport GO:0055085 P:transmembrane transport
References (8) [1] “Possible new genes as revealed by molecular analysis of a 5-kb Escherichia coli chromosomal region 5' to the rpsU-dnaG-rpoD macromolecular-synthesis operon.” Nesin M.et.al. 3297921 [2] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [4] “Intrinsic and extrinsic approaches for detecting genes in a bacterial genome.” Borodovsky M.et.al. 7984428 [5] “The Escherichia coli citrate carrier CitT: a member of a novel eubacterial transporter family related to the 2-oxoglutarate/malate translocator from spinach chloroplasts.” Pos K.M.et.al. 9696764 [6] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996 [7] “Functional identification of ygiP as a positive regulator of the ttdA-ttdB-ygjE operon.” Oshima T.et.al. 16804186 [8] “The L-tartrate/succinate antiporter TtdT (YgjE) of L-tartrate fermentation in Escherichia coli.” Kim O.B.et.al. 17172328

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MKPSTEWWRY LAPLAVIAII ALLPVPAGLE NHTWLYFAVF TGVIVGLILE PVPGAVVAMV 
61:	GISIIAILSP WLLFSPEQLA QPGFKFTAKS LSWAVSGFSN SVIWLIFAAF MFGTGYEKTG 
121:	LGRRIALILV KKMGHRTLFL GYAVMFSELI LAPVTPSNSA RGAGIIYPII RNLPPLYQSQ 
181:	PNDSSSRSIG SYIMWMGIVA DCVTSAIFLT AMAPNLLLIG LMKSASHATL SWGDWFLGML 
241:	PLSILLVLLV PWLAYVLYPP VLKSGDQVPR WAETELQAMG PLCSREKRML GLMVGALVLW 
301:	IFGGDYIDAA MVGYSVVALM LLLRIISWDD IVSNKAAWNV FFWLASLITL ATGLNNTGFI 
361:	SWFGKLLAGS LSGYSPTMVM VALIVVFYLL RYFFASATAY TSALAPMMIA AALAMPEIPL 
421:	PVFCLMVGAA IGLGSILTPY ATGPSPIYYG SGYLPTADYW RLGAIFGLIF LVLLVITGLL 
481:	WMPVVLL

2.A.47.3.3
L-tartrate:succinate antiporter, TtdT (YgjE). (also takes up meso and L-tartrate and succinate; does not transport D-tartrate) (Kim and Unden, 2007). It is induced in the presence of L- or meso tartrate under anaerobic conditions in the presence of TtdR (Kim et al. 2009).

Cross database links:

Gene Ontology

References (8)

External Searches:

Analyze:

2.A.47.3.3L-tartrate:succinate antiporter, TtdT (YgjE). (also takes up meso and L-tartrate and succinate; does not transport D-tartrate) (Kim and Unden, 2007). It is induced in the presence of L- or meso tartrate under anaerobic conditions in the presence of TtdR (Kim et al. 2009).

Cross database links:

Gene Ontology

References (8)

External Searches:

Analyze:

2.A.47.3.3
L-tartrate:succinate antiporter, TtdT (YgjE). (also takes up meso and L-tartrate and succinate; does not transport D-tartrate) (Kim and Unden, 2007). It is induced in the presence of L- or meso tartrate under anaerobic conditions in the presence of TtdR (Kim et al. 2009).