2.A.49.9.1 Fluoride:proton antiporter of 459 aas and 10 TMSs, CLCF, with high selectivity for fluoride over chloride (Brammer et al. 2014). These proteins normally exist as dimers, but the monomers are fully active (Last and Miller 2015).
|
Accession Number: | D2QXG0 |
Protein Name: | Chloride channel core |
Length: | 459 |
Molecular Weight: | 47986.00 |
Species: | Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) [530564] |
Number of TMSs: | 10 |
Substrate |
fluoride, hydron |
---|
1: MQPDSTRHSR MLDIAWRGVR LSLAATVIGV VTGLAVAFFL WSLDQATLLR YEHPWLIYLM
61: PLAGVLVALA YQRLCPQAEA GNNLLLEEIH EPAAGVPLWM APLVLLGTLA THVTGGSAGR
121: EGTAVQMGGS LAHSVGQWLG IERSEQRTFL MAGMAAGFGA VFGTPVAGAI FAIEVLTHGQ
181: LSYRGFLTCL LASIVGDTTT TLCGIGHTEY KIAPWMSAAA GSHLGPLDLV LLLKIVIAAV
241: AFGLMARLFA ELTHRTSALL KRYVPWSLAR PAIGAAVVLL LTAIVASRDY LGLGVMPDPH
301: DPSLMTIAGC FEEGGAGPMS WAWKTVFTAV TVGSGFKGGE VTPLFFIGAA GGNAMGTLLS
361: APLGLLAAVG FVSLFAAATK TPLASTLMGI ELFVHGGDDL VGSGLVIYLA VGCYVASWVS
421: GHASIYRSQR IAVPHHPTDE HLAGRSVGNL HEAPPTASH