| |
---|---|
Accession Number: | P0A769 |
Protein Name: | Manganese transport protein MntH aka YfeP aka B2392 |
Length: | 412 |
Molecular Weight: | 44194.00 |
Species: | Escherichia coli [83333] |
Number of TMSs: | 11 |
Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Multi-pass membrane protein2 |
Substrate | cadmium(2+), cobalt(2+), iron(2+), nickel(2+), zinc(2+), manganese(2+) |
Cross database links:
DIP: | DIP-48004N |
---|---|
RefSeq: | AP_002991.1 NP_416893.1 |
Entrez Gene ID: | 946899 |
Pfam: | PF01566 |
BioCyc: | EcoCyc:YFEP-MONOMER ECOL168927:B2392-MONOMER |
KEGG: | ecj:JW2388 eco:b2392 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015086
F:cadmium ion transmembrane transporter activity
GO:0015078
F:hydrogen ion transmembrane transporter acti...
GO:0030145
F:manganese ion binding
GO:0005384
F:manganese ion transmembrane transporter act...
GO:0015293
F:symporter activity
GO:0015292
F:uniporter activity
GO:0015691
P:cadmium ion transport
GO:0034599
P:cellular response to oxidative stress
GO:0006824
P:cobalt ion transport
GO:0015684
P:ferrous iron transport
GO:0006828
P:manganese ion transport
| |
References (8)[1] “The NRAMP proteins of Salmonella typhimurium and Escherichia coli are selective manganese transporters involved in the response to reactive oxygen.” Kehres D.G.et.al. 10844693 [2] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.” Yamamoto Y.et.al. 9205837 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter.” Makui H.et.al. 10712688 [6] “Determination of transmembrane topology of the Escherichia coli natural resistance-associated macrophage protein (Nramp) ortholog.” Courville P.et.al. 14607838 |
External Searches:
|
Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
|
1: MTNYRVESSS GRAARKMRLA LMGPAFIAAI GYIDPGNFAT NIQAGASFGY QLLWVVVWAN 61: LMAMLIQILS AKLGIATGKN LAEQIRDHYP RPVVWFYWVQ AEIIAMATDL AEFIGAAIGF 121: KLILGVSLLQ GAVLTGIATF LILMLQRRGQ KPLEKVIGGL LLFVAAAYIV ELIFSQPNLA 181: QLGKGMVIPS LPTSEAVFLA AGVLGATIMP HVIYLHSSLT QHLHGGSRQQ RYSATKWDVA 241: IAMTIAGFVN LAMMATAAAA FHFSGHTGVA DLDEAYLTLQ PLLSHAAATV FGLSLVAAGL 301: SSTVVGTLAG QVVMQGFIRF HIPLWVRRTV TMLPSFIVIL MGLDPTRILV MSQVLLSFGI 361: ALALVPLLIF TSDSKLMGDL VNSKRVKQTG WVIVVLVVAL NIWLLVGTAL GL