2.A.55.3.3
Manganese transport protein MntH (YdaR) of 425 aas and 11 TMSs. It is a H+-stimulated, divalent metal cation uptake system involved
in manganese uptake. It can probably also transport cadmium, cobalt, copper
and zinc, but not iron. It may be the predominant transporter of manganese
during logarithmic phase growth. Its transcription is regulated by MntR and AhrC (Que and Helmann 2000; Ogura et al. 2023).
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| Accession Number: | P96593 |
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| Protein Name: | Manganese transport protein MntH |
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| Length: | 425 |
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| Molecular Weight: | 45686.00 |
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| Species: | Bacillus subtilis (strain 168) [224308] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
cadmium(2+), cobalt(2+), copper(2+), zinc(2+), manganese(2+) |
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| Entrez Gene ID: |
938241
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| Pfam: |
PF01566
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| KEGG: |
bsu:BSU04360
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[1] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.” Kunst F. et.al. 9384377
[2] “Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins.” Que Q. et.al. 10760146
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1: MMNKDITAQS PRSKAVQDAL DGKIRGFRGL LPFLGPAFIA AIAYIDPGNF ATNISAGSKY
61: GYMLLWVILF SNIMALLIQS LSAKLGIATG KNLPEVAREE FPKPVSIGLW IQGELVIIAT
121: DLAEFIGAAL GLYLLFGIPM LEASIIAAIG SFAILELQRR GYRSLEAGIA GMLFVVVIAF
181: ALQTFFAKPD AVSVMKGLFV PAFHGTDSVL LAAGILGATV MPHAIYLHSA LTQRRVVGKT
241: DAERKKIFRF EFIDILIAML IAGAINASML IVAAALFFKN GLFVEDLDVA FQQFGHLVSP
301: MSAALFGIGL LVAGLSSSSV GTLSGDVIMQ GFINYRIPLY VRRFITIIPP ILIIASGVNP
361: TTALVLSQVV LSFGIAFALI PLIMFTSNKR IMGSLINAKW ITVVSWLIAV LIVALNVFLI
421: VDTFR