2.A.56.1.10
Transporter for lignin derived aromatic compounds, TarPQM (Salmon et al. 2013). The purple photosynthetic bacterium Rhodopseudomonas palustris is able
to grow photoheterotrophically under anaerobic conditions on a range of
phenylpropeneoid lignin monomers, including coumarate, ferulate, caffeate, and cinnamate. TarPQM is encoded at the
same locus as CouPSTW (TC# 3.A.1.4.11) and several other genes involved in coumarate
metabolism. The periplasmic binding-protein of this system
(TarP) binds coumarate, ferulate, caffeate, and cinnamate
with nanomolar KD values. Thus, R. palustris uses two
redundant but energetically distinct primary and secondary transporters
that both employ high-affinity periplasmic binding-proteins to maximize
the uptake of lignin-derived aromatic substrates from the environment (Salmon et al. 2013).
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| Accession Number: | Q6N8W8 |
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| Protein Name: | TrapT family, dctM subunit, C4-dicarboxylate transport |
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| Length: | 435 |
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| Molecular Weight: | 45876.00 |
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| Species: | Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) [258594] |
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| Number of TMSs: | 10 |
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| Substrate |
trans-2-coumaric acid, cis-caffeic acid, cinnamate, ferulate |
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1: MLTNETVAAI GFVSLFVLML LRVPVGMAMG LVGVTGFGYL TGFEPALKLV GQTTMRTVTD
61: YSFGVIPMFL LMGAFVSASG ISRELFRAGN TIVGHWKGGL GIATIAACGG FAAISGSSVA
121: TAATFSAVAY PEMRRFGYPQ SFSTGVIAVG GTLGAMLPPS TVLAVYGIIT QQDIGKLFIA
181: GILPGLLAIV MHMITIWIIG VARPGFLPAG PKSSWGDRLA AFRDVWSPLL LFLFVIGGLY
241: GGFFIPTEAG AVGAVGAFLI GILRGKLDRE GILQSLLQAT RTAAAVFTVL IGALCFGYFL
301: TITQTPQYVT EFLTGLGIGP YGVLALILLM YLVLGCLMDA MAMVILTVPI VFPVVTALGF
361: DPIWFGIIIV MTVELGLIHP PVGMNVFVIK SVIKDVSMST VFAGVLPFVV TDLIRLVILI
421: AFPIIALWLP MRMIG