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2.A.56.1.2
The 2,3-diketo-L-gulonate (2,3-DKG) transporter, YiaMNO [2,3-KDG is a breakdown product of L-ascorbate] (Thomas et al., 2006)

Accession Number:P37675
Protein Name:YiaN
Length:425
Molecular Weight:45368.00
Species:Escherichia coli [83333]
Number of TMSs:11
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate 2,3-diketogulonate

Cross database links:

RefSeq: AP_004214.1    YP_026232.1   
Entrez Gene ID: 948092   
Pfam: PF06808   
BioCyc: EcoCyc:EG12282-MONOMER   
KEGG: ecj:JW5651    eco:b3578   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006810 P:transport

References (7)

[1] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005.”  Riley M.et.al.   16397293
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Functional characterization of the Escherichia coli K-12 yiaMNO transport protein genes.”  Plantinga T.H.et.al.   14668138
[6] “Deletion of the yiaMNO transporter genes affects the growth characteristics of Escherichia coli K-12.”  Plantinga T.H.et.al.   15870475
[7] “Novel ligands for the extracellular solute receptors of two bacterial TRAP transporters.”  Thomas G.H.et.al.   16385129

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MAVLIFLGCL LGGIAIGLPI AWALLLCGAA LMFWLDMFDV QIMAQTLVNG ADSFSLLAIP 
61:	FFVLAGEIMN AGGLSKRIVD LPMKLVGHKP GGLGYVGVLA AMIMASLSGS AVADTAAVAA 
121:	LLVPMMRSAN YPVNRAAGLI ASGGIIAPII PPSIPFIIFG VSSGLSISKL FMAGIAPGMM 
181:	MGATLMLTWW WQASRLNLPR QQKATMQEIW HSFVSGIWAL FLPVIIIGGF RSGLFTPTEA 
241:	GAVAAFYALF VATVIYREMT FATLWHVLIG AAKTTSVVMF LVASAQVSAW LITIAELPMM 
301:	VSDLLQPLVD SPRLLFIVIM VAILIVGMVM DLTPTVLILT PVLMPLVKEA GIDPIYFGVM 
361:	FIINCSIGLI TPPIGNVLNV ISGVAKLKFD DAVRGVFPYV LVLYSLLVVF VFIPDLIILP 
421:	LKWIN