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|---|---|
| Accession Number: | P47040 |
| Protein Name: | Protein BTN1 |
| Length: | 408 |
| Molecular Weight: | 46383.00 |
| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
| Number of TMSs: | 11 |
| Location1 / Topology2 / Orientation3: | Vacuole membrane1 / Multi-pass membrane protein2 |
| Substrate | |
Cross database links:
| DIP: | DIP-4761N |
|---|---|
| Entrez Gene ID: | 853387 |
| Pfam: | PF02487 |
| KEGG: | sce:YJL059W |
Gene Ontology
GO:0000329
C:fungal-type vacuole membrane
GO:0031301
C:integral to organelle membrane
GO:0015809
P:arginine transport
GO:0051453
P:regulation of intracellular pH
GO:0007034
P:vacuolar transport
GO:0007033
P:vacuole organization
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References (8)[1] “The subcellular location of the yeast Saccharomyces homologue of the protein defective in the juvenile form of Batten disease.” Croopnick J.B.et.al. 9753630 [2] “Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.” Galibert F.et.al. 8641269 [3] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.” Hu Y.et.al. 17322287 [4] “BTN1, a yeast gene corresponding to the human gene responsible for Batten's disease, is not essential for viability, mitochondrial function, or degradation of mitochondrial ATP synthase.” Pearce D.A.et.al. 9219333 [5] “Action of BTN1, the yeast orthologue of the gene mutated in Batten disease.” Pearce D.A.et.al. 10319861 [6] “The yeast model for Batten disease: mutations in BTN1, BTN2, and HSP30 alter pH homeostasis.” Chattopadhyay S.et.al. 11053386 [7] “A role in vacuolar arginine transport for yeast Btn1p and for human CLN3, the protein defective in Batten disease.” Kim Y.et.al. 14660799 [8] “Interaction among Btn1p, Btn2p, and Ist2p reveals potential interplay among the vacuole, amino acid levels, and ion homeostasis in the yeast Saccharomyces cerevisiae.” Kim Y.et.al. 15701790
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSDKSHQIYC YFWLFGLINN VLYVVILSAA VDIVGPTLPK SLVLLADIFP SLAIKLCSPF 61: FIDRIKYSYR IWSLITMSCL GMFLVSFKNL FVCLLGISFA SISSGFGEVT FLQLTHYYKQ 121: ISLNGWSSGT GGAGIIGGAS YMFLTSIFKV PVKLTLLVFS LLPFAFLFYF KLESNDTNLT 181: YQSLQQIDEA EDDQLVPFPV AFTHTNASQS LYSTRQHILQ TVKRLRRLVF PYMVPLTTVY 241: LFEYLINQAV APTLLFPING DERSKSMPFF FHKYRDIYVT YGTLYQLGVF ISRSFGHLMR 301: MRSLYILAFL QGVNLCITVL QSWFYVTHSP WAVMILIFYE GFLGGASYVN TFLNILEQED 361: PDETEFAMGA VSIADSFGVF LAALLGLGLE PKLCRHQIAD DRPWCRME