2.A.60.1.25
facilitative organic anion carrier, Slco1a6 of 670 aas and 12 TMSs. Also called Kidney-specific organic anion-transporting polypeptide 5 (Oatp5). Transports bile acids such as taurocholic acid and other anionic compounds (Tian et al. 2015).
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| Accession Number: | Q99J94 |
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| Protein Name: | Solute carrier organic anion transporter family member 1A6 |
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| Length: | 670 |
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| Molecular Weight: | 74145.00 |
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| Species: | Mus musculus (Mouse) [10090] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
taurocholic acid |
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1: MGEPGKRVGI HRVRCFAKIK VFLLALIWAY ISKILSGVYM STMLTQLERQ FNISTSIVGL
61: INGSFEMGNL LVIVFVSYFG TKLHRPIMIG VGCAVMGLGC FIISLPHFLM GRYEYETTIS
121: PTSNLSSNSF LCVENRSQTL KPTQDPAECV KEIKSLMWIY VLVGNIIRGI GETPIMPLGI
181: SYIEDFAKSE NSPLYIGILE VGKMIGPILG YLMGPFCANI YVDTGSVNTD DLTITPTDTR
241: WVGAWWIGFL VCAGVNVLTS IPFFFFPKTL PKEGLQDNGD GTENAKEEKH RDKAKEENQG
301: IIKEFFLMMK NLFCNPIYML CVLTSVLQVN GVANIVIYKP KYLEHHFGIS TAKAVFLIGL
361: YTTPSVSAGY LISGFIMKKL KITLKKAAII ALCLFMSECL LSLCNFMLTC DTTPIAGLTT
421: SYEGIQQSFD MENKFLSDCN TRCNCLTKTW DPVCGNNGLA YMSPCLAGCE KSVGTGANMV
481: FQNCSCIRSS GNSSAVLGLC KKGPDCANKL QYFLIITVFC CFFYSLATIP GYMVFLRCMK
541: SEEKSLGIGL QAFFMRLFAG IPAPIYFGAL IDRTCLHWGT LKCGEPGACR TYEVSSFRRL
601: YLGLPAALRG SIILPSFFIL RLIRKLQIPG DTDSSEIELA ETKPTEKESE CTDMHKSSKV
661: ENDGELKTKL