2.A.60.1.26
OATP1C1 of 710 aas and 12 TMSs. Transports pro-thyroid hormone T4 with high affinity (Nele Bourgeois et al. 2016).
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| Accession Number: | F1NQ63 |
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| Protein Name: | Solute carrier organic anion transporter family member |
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| Length: | 710 |
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| Molecular Weight: | 77689.00 |
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| Species: | Gallus gallus (Chicken) [9031] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MEISSKENAQ LFSNNAVLPV DRSSFKSESS TSKEKQSCCG GIKIFLGALS FVYFAKALSG
61: SYLKSTITQI ERRFDIPSSL VGVIDGSFEI GNLLIIVFVS YFGAKLHRPR IIGAGCLIMS
121: AGTFLIAMPQ FFMGRYQYER FPSTINSTVS ISPCLQEKSQ TPLSALEKSQ AKVNAGCEKA
181: GSSMWIYVFL GNLLRGIGET PIQPLGITYI DDYAIEENAA LYIGCVQTLA IIGPIFGFLL
241: GSLCAKLYVD IGFVDLDSIT ITHKDVQWVG AWWLGYLIAG VISVLAGIPF WFLPKHLPKP
301: ESRKDSSTSS EQSKFITQDN KEQQKSYQPQ MKVAEMAKDF LPSLKNLFGN PVYSLFLCAS
361: ILHFNSLIGM VTYKPKYIEQ QYGQTSSKTN FVIGLINIPA VAFGIFSGGL IMKKFRINVL
421: GAAKISLGSS FFGYLLLLSL FAMGCENSDV AGLTVSYHGT KQKVGYEQGL FSECNLGCMC
481: SQNDWDPICG ENGITYISAC LAGCQASNGS GKNTVFFNCS CVGIMASPSR SSSAVMGPCQ
541: KGNECPKMFL YFLVISVITS YTLSVGGTPG YILLLRCIKP HLKSFALGIY TLAIRVLAGI
601: PAPVYFGVAI DTTCLKWGRK RCGGRGACRL YDSSALRYVY LGLTLVLGTV SIFFSIAVLW
661: VLRKRSALQD ETLSANGERD TCVTKSRKDN FVNSDHLIQT TYWPEKETRL