2.A.60.1.28
Thyroid hormone transporter, OATP1C1, of 710 aas and 12 TMSs in a clear 3 + 3 + 3 + 3 arrangement (Zada et al. 2017).
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| Accession Number: | B3DJD4 |
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| Protein Name: | Solute carrier organic anion transporter family member |
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| Length: | 710 |
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| Molecular Weight: | 78083.00 |
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| Species: | Danio rerio (Zebrafish) [7955] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
thyroid hormone |
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1: MPRNCMKESS SPKENEIFLW RMDLPNKERR SPENSPSSSR RCCSSFKMFL VALSFAYFSK
61: ALSGSYMKST ITQLERRFDI PSYLIGVIDG SFEIGNLLVI AFVSYFGAKL HRPKIIAIGC
121: LLMSLGTFLI ALPHFIIGRY KFETSIRLSV NSSSSLSPCS LSSAEPSTSS VPSTGCEHES
181: RLSMWIYVFL GNILRGIGET PVQPLGISYI DDHALEENAA FYIGCVQTIS VIGPVFGYLL
241: GSVCAKIYVD IGFVNMESIS ITPGDARWVG AWWLGYLIAG FITLLSAVPF WFLPKSLPLP
301: ERRLSKYSPE RNSFIKDSAL LEHKYQADEP ANFLEMAKDF LPTLRSLLGN PVYFLYLCVT
361: IIQFNSLIGM VTYKPKYIEQ HYGQSASKAN FLMGVINIPA VALGMFSGGV IMKKFKLSIM
421: GAAKFALGTS LLGYFLSLFF FSMGCENASV AGITMSYNGT ESLFMADGSL RASCNAACHC
481: PEKNWDPVCG EDGLTYVSPC LAGCRTSHGS GMDTVFEQCS CIGVGNQTAT AGQCNNRESC
541: HRIFPYFLAL SVITSFIISL GGTPGYMLLI RCIKPQLKSL ALGFHTLTTR TLAGIPAPIY
601: FGAIIDTTCL KWGHKKCGGR GACRIYNTAA YRIAYLGLTL GLRTVSFFLC ILGLLVLRRH
661: VQKQERSTMV NGGSAAAGEL QALRKEENNS CNSEQCPQNT DYDPERETRL