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2.A.66.1.22
Quinolone:H+ antiporter, EmmdR. Substates include benzalkonium chloride, norfloxacin, ciprofloxacin, levofloxacin, ethidium bromide, acriflavine, rhodamine 6G and trimethoprim.

Accession Number:D5CJ69
Protein Name:MATE efflux family protein
Length:462
Molecular Weight:50233.00
Species:Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCDC 279-56) [716541]
Number of TMSs:11
Substrate rhodamine 6G, hydron, levofloxacin, ciprofloxacin, quinolone, norfloxacin, trimethoprim, benzalkonium chloride, 3,6-diamino-10-methylacridinium chloride, ethidium bromide

Cross database links:

Entrez Gene ID: 9127720   
Pfam: PF01554   
KEGG: enc:ECL_03329   

Gene Ontology

GO:0016020 C:membrane
GO:0015297 F:antiporter activity
GO:0015238 F:drug transmembrane transporter activity

References (1)

[1] “Complete genome sequence of Enterobacter cloacae subsp. cloacae type strain ATCC 13047.”  Ren Y.et.al.   20207761

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRTPWYAKRK SYRVLFWREI TPLAVPIFLE NTCVLLMGVL STFLVSWLGK EAMAGVGLAD 
61:	SFNMVVMSFF AAIDLGTTVV VAFSLGKLDP KRAREAARQS LMIMTLFSII LAAVIHYFGK 
121:	EIIDFVAGEA TNEVKDLALT YLEMTVLSYP AAAIALIGSG ALRGAGNTKI PLLINGGMNI 
181:	LNIMISSVLI YGVFSWEGMG FVGAGLGLTI SRYIGAAAIL GVLMAGITPS LRLTLKSYFR 
241:	PFNFAIIWEV MGIGIPASIE SVLFNAGKLL TQMFVAGMGT DVIAGNFIAF SIASLINLPG 
301:	NALGSASTII TGKRLGKGQI GQAERQLRHV FWLSTIGLTI IAWGSAPFAG LMASFYTHED 
361:	DVKEVVKILI WLNAAFMPIW AASWVLPAGL KGARDARFAM WVSMLGMWGC RVVAGYTLGV 
421:	MLGMGVVGVW LGMFLDWAVR GALFYWRMVS GRWLWKYPRH NA