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2.A.66.1.4 DNA damage-inducible protein F, DinF. Protects against oxidative stress and bile salts, possibly by pumping relevant compounds out of the cytoplasm (Rodríguez-Beltrán et al. 2012).
Accession Number:	P28303
Protein Name:	DinF aka B4044
Length:	459
Molecular Weight:	49646.00
Species:	Escherichia coli [83333]
Number of TMSs:	13
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	bile acid

RefSeq:	AP_004545.1 NP_418468.3
Entrez Gene ID:	948554
Pfam:	PF01554
BioCyc:	EcoCyc:DINF-MONOMER ECOL168927:B4044-MONOMER
KEGG:	ecj:JW4004 eco:b4044
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0015297 F:antiporter activity GO:0015238 F:drug transmembrane transporter activity GO:0006855 P:drug transmembrane transport
References (4) [1] “Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.” Blattner F.R.et.al. 8265357 [2] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [4] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MPPGVAVCFS SLFIRLVCMA FLTSSDKALW HLALPMIFSN ITVPLLGLVD TAVIGHLDSP 
61:	VYLGGVAVGA TATSFLFMLL LFLRMSTTGL TAQAYGAKNP QALARTLVQP LLLALGAGAL 
121:	IALLRTPIID LALHIVGGSE AVLEQARRFL EIRWLSAPAS LANLVLLGWL LGVQYARAPV 
181:	ILLVVGNILN IVLDVWLVMG LHMNVQGAAL ATVIAEYATL LIGLLMVRKI LKLRGISGEM 
241:	LKTAWRGNFR RLLALNRDIM LRSLLLQLCF GAITVLGARL GSDIIAVNAV LMTLLTFTAY 
301:	ALDGFAYAVE AHSGQAYGAR DGSQLLDVWR AACRQSGIVA LLFSVVYLLA GEHIIALLTS 
361:	LTQIQQLADR YLIWQVILPV VGVWCYLLDG MFIGATRATE MRNSMAVAAA GFALTLLTLP 
421:	WLGNHALWLA LTVFLALRGL SLAAIWRRHW RNGTWFAAT

2.A.66.1.4
DNA damage-inducible protein F, DinF. Protects against oxidative stress and bile salts, possibly by pumping relevant compounds out of the cytoplasm (Rodríguez-Beltrán et al. 2012).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

2.A.66.1.4DNA damage-inducible protein F, DinF. Protects against oxidative stress and bile salts, possibly by pumping relevant compounds out of the cytoplasm (Rodríguez-Beltrán et al. 2012).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

2.A.66.1.4
DNA damage-inducible protein F, DinF. Protects against oxidative stress and bile salts, possibly by pumping relevant compounds out of the cytoplasm (Rodríguez-Beltrán et al. 2012).