2.A.66.1.42 Paralytic shellfish toxin (PST; including saxitoxin (STX)) exporter, SxtM, of 464 aas (Soto-Liebe et al. 2013). These toxins, which block Na+ channels, are produced by cyanobacteria and dinoflagellates, and >30 such natural alkaloids are known (Soto-Liebe et al. 2012).
|
Accession Number: | J7KFV5 |
Protein Name: | SxtM |
Length: | 464 |
Molecular Weight: | 49776.00 |
Species: | Cylindrospermopsis raciborskii MVCC14 [940191] |
Number of TMSs: | 12 |
Substrate |
decarbamoylsaxitoxin |
---|
1: LAEVTSKGYK SELRSEARVS LQLAIPLVVV ETCETSINTV DVVMMGLLGT QVLAGGALGV
61: IAFLTLLFTC SSTLLAGGAQ AAEAFGANNI DRLCRIASGN LWLATALSLP AMFMLWHGDT
121: ILLLFGQQQS NVLLAKTYLH SIVWGFPAAL GIKILRGIAS AVNVPQLVTV TMLVGPVLNA
181: PANYVLMFGK FGLPELGLAG IGWASTLVFW ISFLVGVVLL IFSPKVRDYQ LFRYLHQFDR
241: QTVVEIFQTG WPMGFLLGVE SAVLGLSAWL AGYLGTVTLA AHEIAIQTAE LAIVIPLGIG
301: NVTVTRVGQT MGEKNPLGAR RAALIGIMIG GIYASAVALI FWLFPYQIAG LYLKINDPES
361: MEAVKTATTF LVLAGLFQFF YSIQIIIVGA LIGLQDTFMP LLMNLVSWGL GLAVSYYMGT
421: ILGWGGMGIW LGMVLSPLLS GVILMVRFYQ EIAKKIANSD DGEE