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Accession Number: | Q93HR7 |
Protein Name: | VmrA |
Length: | 447 |
Molecular Weight: | 49314.00 |
Species: | Vibrio parahaemolyticus [670] |
Number of TMSs: | 12 |
Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
Substrate | sodium(1+), tetraphenylphosphonium, 3,6-diamino-10-methylacridinium chloride, thiamine(1+) diphosphate, nifedipine, ethidium |
Cross database links:
Pfam: | PF01554 |
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Gene Ontology
GO:0016020
C:membrane
GO:0015297
F:antiporter activity
GO:0015238
F:drug transmembrane transporter activity
GO:0006855
P:drug transmembrane transport
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References (1)[1] “VmrA, a member of a novel class of Na(+)-coupled multidrug efflux pumps from Vibrio parahaemolyticus.” Chen J.et.al. 11751837
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MQNSIYKQFW KYTIPTVAAM LVNGLYQVVD GIFIGRYVGA YGLAGINVAW PVIGSILGIG 61: MMVGVGTGAL TSIKQGEQDQ QGAKRVLTTG LLFLLALMPI VATILFFLAD DFIRWQGAQG 121: RVYELGLQYL QILIVACIFH LALLRFHSCY VTTQPNLATI LMVIGAIINI VLDYVFIAWM 181: NWELTGAAIA TALAQMVVTV LGVGYFFSSK AKLRLTFREL KVQLDAIPKI VLIGTSSFFM 241: YAYGSTMGSS AQRVIRTIRQ PAFDRRYAIL GYIVTVYYLV AEGIANGMQP LVSYNHGARK 301: QDNIRKLLQI AMGTSVLGGV VFVVLMNLFP YQLVSVFNDA DQQLIESAVV GIRLHMFALF 361: LDGFLVVAGA YYQSVNKGSK AMFVTVGNML IQLPFLFIMP KLLGVTGIWI AFPLSNIALS 421: LVVMSMLWRD IKKLMVDRPV EPSIQAS