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2.A.7.12.7
Golgi UDP-N-acetylglucosamine transporter (Ishida et al., 1999a). Conserved Glu-47 and Lys-50 residues are critical for UDP-N-acetylglucosamine/UMP antiport activity of the mouse Golgi-associated transporter (Toscanini et al. 2019). Colorectal cancer with low SLC35A3 is associated with immune infiltrates and poor prognosis (Lu et al. 2024).  Potential interaction partners have been identified (Wiktor et al. 2021).

Accession Number:Q9Y2D2
Protein Name:UDP-N-acetylglucosamine transporter
Length:325
Molecular Weight:35985.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate UDP-N-acetyl-alpha-D-glucosamine

Cross database links:

RefSeq: NP_036375.1   
Entrez Gene ID: 23443   
Pfam: PF04142   
OMIM: 605632  gene
KEGG: hsa:23443    hsa:23443   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0005351 F:sugar:hydrogen symporter activity
GO:0005462 F:UDP-N-acetylglucosamine transmembrane trans...
GO:0006047 P:UDP-N-acetylglucosamine metabolic process
GO:0015788 P:UDP-N-acetylglucosamine transport
GO:0005462 F:UDP-N-acetylglucosamine transmembrane transporter activity

References (6)

[1] “Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter.”  Ishida N.et.al.   10393322
[2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[3] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005
[4] “Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter.”  Ishida N.et.al.   10393322
[5] “Complete sequencing and characterization of 21,243 full-length human cDNAs.”  Ota T.et.al.   14702039
[6] “The full-ORF clone resource of the German cDNA consortium.”  Bechtel S.et.al.   17974005

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MFANLKYVSL GILVFQTTSL VLTMRYSRTL KEEGPRYLSS TAVVVAELLK IMACILLVYK 
61:	DSKCSLRALN RVLHDEILNK PMETLKLAIP SGIYTLQNNL LYVALSNLDA ATYQVTYQLK 
121:	ILTTALFSVS MLSKKLGVYQ WLSLVILMTG VAFVQWPSDS QLDSKELSAG SQFVGLMAVL 
181:	TACFSSGFAG VYFEKILKET KQSVWIRNIQ LGFFGSIFGL MGVYIYDGEL VSKNGFFQGY 
241:	NRLTWIVVVL QALGGLVIAA VIKYADNILK GFATSLSIIL STLISYFWLQ DFVPTSVFFL 
301:	GAILVITATF LYGYDPKPAG NPTKA