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2.A.7.15.2
The Golgi transporter, SQV-7. Transports UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose (Gal). These nucleotide sugars are competitive, alternate, noncooperative substrates. Mutant sqv-7 missense alleles result in severe reductions of these three transport activities. SQV-7 did not transport CMP-sialic acid, GDP-fucose, UDP-N-acetylglucosamine, UDP-glucose, or GDP-mannose (Berninsone et al. 2001).

Accession Number:Q18779
Protein Name:SQV-7 aka yk46f1.5 aka C52E12.3
Length:329
Molecular Weight:36893.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Golgi apparatus membrane1 / Multi-pass membrane protein2
Substrate UDP-N-acetyl-alpha-D-galactosamine 4-sulfate, UDP-alpha-D-galactose

Cross database links:

RefSeq: NP_495436.1   
Entrez Gene ID: 174145   
Pfam: PF03151   
KEGG: cel:C52E12.3   

Gene Ontology

GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0008643 P:carbohydrate transport
GO:0009792 P:embryonic development ending in birth or eg...

References (2)

[1] “Genome sequence of the nematode C. elegans: a platform for investigating biology.”  The C. elegans sequencing consortiumet.al.   9851916
[2] “SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP-N-acetylgalactosamine, and UDP-galactose.”  Berninsone P.et.al.   11259660

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MTSTVQSPLY SRVFSAVFYG VISVLIVFVN KILLTNYKFP SFLFVGVGQM MATILILFFA 
61:	KMFRIVQFPS LDSSIPRKIM PLPLLYFFNL ISGLGGTQMI NLPMFTVLRR FSILMTMILE 
121:	FYILNVKASK AVKISVGLMI GGSFIAAIYD LSFDALGYTM IFINNICTAA LGVYTKQKLD 
181:	AKDLGKYGLM FYNCLFMLLP ALCVVQYTGD LDRAYSFMLS DSMTSSVWTC FLLSCICGFV 
241:	LNYSLVLCTH HNSALTTTCV GPIKNLFVTY VGMFSSGDYV FQWANFTGIN VSVFGSILYT 
301:	YVTFRSKSTT ISYKPLPMTM PIDVHKPRN