2.A.7.20.4
Chloroplastic chloroquine resistance transporter-1 of 447 aas and 10 TMSs, Clt-1. Involved in thiol transport from the
plastid to the cytosol. Transports both glutathione (GSH) and
its precursor, gamma-glutamylcysteine (gamma-EC). Exhibits some
functional redundancy with CLT3 in maintaining the root GSH pool (Maughan et al. 2010).
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| Accession Number: | Q058P6 |
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| Protein Name: | Protein CLT1, chloroplastic |
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| Length: | 447 |
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| Molecular Weight: | 47925.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Plastid1 / Multi-pass membrane protein2 |
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| Substrate |
chloroquine |
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1: MATTSSDRLI AGLTASIGSI ESRYANPAQS VSLICRNQIN GAPPIVLRSS RRSRLWLIEA
61: IPPAKSWNGS NDGDEDIKKS DTRNYAIGGT GGHAVAGKDD RTMEIVIAAA TTAALGVGNR
121: VLYKLALIPL KQYPFFLAQL STFGYVAVYF SILYFRYRAG IVTKEMLSVP KLPFLIVGVL
181: ESLALAAGMA AASNLSGPST TVLSQTFLVW QILFSIIFLG RRYRINQILG CTLVAFGVIV
241: SVASGSGAAH SFKDTGILWS LLMVFSFLLQ GADTVMKEVI FLDSKKRLKG ASLDLFVVNS
301: YGSIFQVICI ALLLPFLSKL WGIPFNQLPS YIRDGGACFL NIGSRITGCE GAPLLPVMFV
361: MMNMAYNISL LRLIKISSAV VSSLASTVSV PIAVYCFTLP LPYLGVASTL PRGFVAGTII
421: LVVGMLLYAW TPSTNTSDSI IPSPPST