2.A.7.3.75
SepJ, a novel composite protein of 751 aas needed for cellular filament integrity, proper heterocyst development and N2 fixation. It has a C-terminal DME family domain (Flores et al., 2007). Mullineaux et al. (2008) have proposed that this protein (SepJ; FraG) may be a channel-forming protein for transfer of metabolites between cells. However, it may instead be a polar amino acid transporter since DmeA of Synecococcus (TC# 2.A.7.3.58) complements a defect in SepJ (E. Flores, unpubished observations).
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| Accession Number: | Q8YUK6 |
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| Protein Name: | SepJ |
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| Length: | 751 |
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| Molecular Weight: | 81389.00 |
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| Species: | Anabaena sp. (strain PCC 7120) [103690] |
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| Number of TMSs: | 10 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MGRFEKRPDN DPRVRGELSR AAETALWAVV EDLESLQQNV LRSFQEEIKK LQTEKDRLTD
61: EVQQLIEEKE HLQEVRRITE QQVLIRQLSE ALAKHICSQL QSSLAKIANQ TESQIAALKS
121: AQSIGPAIEN NEQVEKMLGS LDDNLTIAFN SLQQELKNYQ SNLSQQLSRM YNQQQQGETI
181: VEELIDRLRG ELTRAIQETS TAKAQLSPPT VLQPPELQPP SSPVVVNLSP PTVLQFPDQQ
241: SPNPLQASTP LEETSTTKPS VSITPPEKST PVTIVPPPQE TRPETKSVIP KVSPDSETKL
301: QSSQEKAAEP SSVINRELSA GAAKSPLTPE KPPEPISTSK TKFSPSSEKP PEPISTSKTK
361: FSPSSEKPPE PVSVLSRDSS ASKASTPPPA PVVRRGSTPS SSRSRKSSNL SPVQVGFLLV
421: VLSTVMTALY NVVLKGMFYK TSQLSAMLEV AGLISPTLGN IMLILTLRLM VVVPLMILLA
481: PMMYPQVWQD LQNLKQSLGN NQSGSRSQPQ RFVQLMFASG CFLFLSQVLI YLAIGQVPTG
541: VAIALFFVYP LINGVLSWLL FRDRPGVFRA SAIGAIFCGE VLVFAGATST GIGTTPLGSI
601: TAILAGAAFA CYLILTRVCA AKVHPVSLSL INFVTMLGLS FIFLMIPLPE NWSLVVDPSK
661: LLEIVLSAFI LGALTLLSYV FSHIGINKLG GLRSAIISAS VPILTVILAG LVLQETLNIA
721: QIFGVLFVTF GAIAFGIGKI QNPNKPANAE G