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2.A.7.6.1
Rhamnose:H+ symporter, RhaT (Garcia-Martin et al. 1992) of 344 aas and 10 TMSs in a 5 + 5 TMS arrangement (Tate and Henderson 1993).  IT belongs to the TMEM144 family. Transcriptional regulation of rhaT is due to the RhaS activator, and L-rhamnose, L-lyxose and L-mannose activate (Vía et al. 1996).

Accession Number:P27125
Protein Name:RhaT aka B3907
Length:344
Molecular Weight:37320.00
Species:Escherichia coli [83333]
Number of TMSs:10
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate hydron, alpha-L-rhamnopyranose

Cross database links:

RefSeq: AP_003901.1    NP_418343.1   
Entrez Gene ID: 948398   
Pfam: PF06379   
BioCyc: EcoCyc:RHAT-MONOMER    ECOL168927:B3907-MONOMER   
KEGG: ecj:JW3878    eco:b3907   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015153 F:rhamnose transmembrane transporter activity
GO:0015293 F:symporter activity
GO:0015762 P:rhamnose transport

References (8)

[1] “Mapping, cloning, expression, and sequencing of the rhaT gene, which encodes a novel L-rhamnose-H+ transport protein in Salmonella typhimurium and Escherichia coli.”  Tate C.G.et.al.   1551902
[2] “Nucleotide sequence of the rhaR-sodA interval specifying rhaT in Escherichia coli.”  Garcia C.et.al.   1339463
[3] “Analysis of the Escherichia coli genome. III. DNA sequence of the region from 87.2 to 89.2 minutes.”  Plunkett G. IIIet.al.   8346018
[4] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[5] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[6] “Membrane topology of the L-rhamnose-H+ transport protein (RhaT) from enterobacteria.”  Tate C.G.et.al.   8262918
[7] “Transcriptional regulation of the Escherichia coli rhaT gene.”  Via P.et.al.   8757746
[8] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MSNAITMGIF WHLIGAASAA CFYAPFKKVK KWSWETMWSV GGIVSWIILP WAISALLLPN 
61:	FWAYYSSFSL STRLPVFLFG AMWGIGNINY GLTMRYLGMS MGIGIAIGIT LIVGTLMTPI 
121:	INGNFDVLIS TEGGRMTLLG VLVALIGVGI VTRAGQLKER KMGIKAEEFN LKKGLVLAVM 
181:	CGIFSAGMSF AMNAAKPMHE AAAALGVDPL YVALPSYVVI MGGGAIINLG FCFIRLAKVK 
241:	DLSLKADFSL AKSLIIHNVL LSTLGGLMWY LQFFFYAWGH ARIPAQYDYI SWMLHMSFYV 
301:	LCGGIVGLVL KEWNNAGRRP VTVLSLGCVV IIVAANIVGI GMAN