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2.A.76.1.4 O-aetylserine/cysteine/azaserine exporter, EamB or YfiK of 195 aas and 6 TMSs (Franke et al., 2003). High level cell-free expression and specific labeling of EamB of E. coli has been achieved (Klammt et al. 2004).
Accession Number:	P38101
Protein Name:	YfiK aka B2578
Length:	195
Molecular Weight:	21248.00
Species:	Escherichia coli [83333]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	cysteine, azaserine

RefSeq:	AP_003164.1 NP_417073.1
Entrez Gene ID:	947065
Pfam:	PF01810
BioCyc:	EcoCyc:EG12445-MONOMER ECOL168927:B2578-MONOMER
KEGG:	ecj:JW2562 eco:b2578
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0006865 P:amino acid transport
References (5) [1] “Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.” Yamamoto Y.et.al. 9205837 [2] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [4] “YfiK from Escherichia coli promotes export of O-acetylserine and cysteine.” Franke I.et.al. 12562784 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTPTLLSAFW TYTLITAMTP GPNNILALSS ATSHGFRQST RVLAGMSLGF LIVMLLCAGI 
61:	SFSLAVIDPA AVHLLSWAGA AYIVWLAWKI ATSPTKEDGL QAKPISFWAS FALQFVNVKI 
121:	ILYGVTALST FVLPQTQALS WVVGVSVLLA MIGTFGNVCW ALAGHLFQRL FRQYGRQLNI 
181:	VLALLLVYCA VRIFY

2.A.76.1.4
O-aetylserine/cysteine/azaserine exporter, EamB or YfiK of 195 aas and 6 TMSs (Franke et al., 2003). High level cell-free expression and specific labeling of EamB of E. coli has been achieved (Klammt et al. 2004).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.76.1.4O-aetylserine/cysteine/azaserine exporter, EamB or YfiK of 195 aas and 6 TMSs (Franke et al., 2003). High level cell-free expression and specific labeling of EamB of E. coli has been achieved (Klammt et al. 2004).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

2.A.76.1.4
O-aetylserine/cysteine/azaserine exporter, EamB or YfiK of 195 aas and 6 TMSs (Franke et al., 2003). High level cell-free expression and specific labeling of EamB of E. coli has been achieved (Klammt et al. 2004).