Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


2.A.8.1.3
D-Fructuronate/D-gluconate:H+ symporter, GntP (Bates Utz et al., 2004)

Accession Number:P0AC94
Protein Name:High-affinity gluconate transporter gntP aka Gnt-III system
Length:447
Molecular Weight:47138.00
Species:Escherichia coli [83333]
Number of TMSs:13
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate hydron, D-fructofuranuronic acid, D-gluconate

Cross database links:

RefSeq: AP_004813.1    NP_418741.1   
Entrez Gene ID: 948848   
Pfam: PF02447   
BioCyc: EcoCyc:GNTP-MONOMER    ECOL168927:B4321-MONOMER   
KEGG: ecj:JW4284    eco:b4321   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0015128 F:gluconate transmembrane transporter activity
GO:0019521 P:D-gluconate metabolic process
GO:0015725 P:gluconate transport

References (5)

[1] “The gntP gene of Escherichia coli involved in gluconate uptake.”  Klemm P.et.al.   8550444
[2] “Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.”  Burland V.D.et.al.   7610040
[3] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[5] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MHVLNILWVV FGIGLMLVLN LKFKINSMVA LLVAALSVGM LAGMDLMSLL HTMKAGFGNT 
61:	LGELAIIVVF GAVIGKLMVD SGAAHQIAHT LLARLGLRYV QLSVIIIGLI FGLAMFYEVA 
121:	FIMLAPLVIV IAAEAKIPFL KLAIPAVAAA TTAHSLFPPQ PGPVALVNAY GADMGMVYIY 
181:	GVLVTIPSVI CAGLILPKFL GNLERPTPSF LKADQPVDMN NLPSFGVSIL VPLIPAIIMI 
241:	STTIANIWLV KDTPAWEVVN FIGSSPIAMF IAMVVAFVLF GTARGHDMQW VMNAFESAVK 
301:	SIAMVILIIG AGGVLKQTII DTGIGDTIGM LMSHGNISPY IMAWLITVLI RLATGQGVVS 
361:	AMTAAGIISA AILDPATGQL VGVNPALLVL ATAAGSNTLT HINDASFWLF KGYFDLSVKD 
421:	TLKTWGLLEL VNSVVGLIIV LIISMVA