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2.A.86.1.2
Putative permease, YhhT (a member of the PurR purine regulon) with 7 TMSs in a 2 + 1 + 4 TMS arrangement.

Accession Number:P0AGM0
Protein Name:UPF0118 inner membrane protein yhhT
Length:349
Molecular Weight:38522.00
Species:Escherichia coli (strain K12) [83333]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 947980   
Pfam: PF01594   
KEGG: ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474    ecj:JW5680    eco:b3474   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane

References (40)

[1] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[5] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[6] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[7] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[8] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[9] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[10] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[11] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[12] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[13] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[14] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[15] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[16] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[17] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[18] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[19] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[20] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[21] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[22] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[23] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[24] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[25] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[26] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[27] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[28] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[29] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[30] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[31] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[32] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[33] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[34] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[35] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[36] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996
[37] “Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.”  Sofia H.J.et.al.   8041620
[38] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[39] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[40] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	METPQPDKTG MHILLKLASL VVILAGIHAA ADIIVQLLLA LFFAIVLNPL VTWFIRRGVQ 
61:	RPVAITIVVV VMLIALTALV GVLAASFNEF ISMLPKFNKE LTRKLFKLQE MLPFLNLHMS 
121:	PERMLQRMDS EKVVTFTTAL MTGLSGAMAS VLLLVMTVVF MLFEVRHVPY KMRFALNNPQ 
181:	IHIAGLHRAL KGVSHYLALK TLLSLWTGVI VWLGLELMGV QFALMWAVLA FLLNYVPNIG 
241:	AVISAVPPMI QVLLFNGVYE CILVGALFLV VHMVIGNILE PRMMGHRLGM STMVVFLSLL 
301:	IWGWLLGPVG MLLSVPLTSV CKIWMETTKG GSKLAILLGP GRPKSRLPG