| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
2.A.87.1.1 | The riboflavin uptake transporter, RibU (may also transport roseoflavin and flavin mononucleotide (FMN)) (Burgess et al., 2006). Substrates noted above bind RibU with nM (Vitamin B2 with 0.6 nM) affinity with 1:1 stoichiometry; FAD does not bind (Duurkens et al., 2007). | Bacteria |
Bacillota | RibU of Lactococcus lactis (AAY43361) |
|
2.A.87.1.2 | Riboflavin transporter RibU (Riboflavin ECF transporter S component RibU or YpaA). Regulated by FMN riboswitch (Rodionov et al. 2009). RibU-mediated riboflavin uptake was sensitive to protonophores and reduced in the absence of glucose, demonstrating that the protein requires metabolic energy for substrate translocation (Vogl et al. 2007). | Bacteria |
Bacillota | RibU of Bacillus subtilis (P50726) |
|
2.A.87.1.3 | Riboflavin ECF Transporter, RibU. The substrate-binding component (S) has been solved by x-ray crystallography (Zhang et al., 2010). | Bacteria |
Bacillota | RibU of Staphylococcus aureus (D3EWM9) |
|
2.A.87.1.4 | The riboflavin transporter of 203 aas and 5 TMSs, RibU or EcfS. Mediates
riboflavin and maybe also FMN, FAD and roseoflavin uptake (and efflux) (Light et al. 2018). Interacts with the energy-coupling
factor (ECF) module, EcfAA'T, which energizes transport of a number
of different substrates, each with its own EcfS subunit. Does not use an extracytoplasmic receptor (Karpowich et al. 2015). It provides extracellur FAD for an extracellular electron transfer process in firmicutes (Light et al. 2018). | Bacteria |
Bacillota | Riboflavin transporter of Listeria monocytogenes |
|
2.A.87.2.1 | Pantothenate transporter PanT (Pantothenic acid ECF transporter S component PanT). A similar pantothenate transporter, also called PanT, has been characterized in Lactobacillus brevis (Zhang et al. 2014). | Bacteria |
Bacillota | PanT of Leuconostoc mesenteroides (Q03YI6)
|
|
2.A.87.2.3 | Putative Thiamine Transporter, ThiA (Duf165; YuaJ) (187 aas; 6 TMSs) | Bacteria |
Bacillota | ThiA of Streptococcus mitis (F9LXW4) |
|
2.A.87.3.1 | Uncharacterized protein of 172 aas and 5 TMSs | Bacteria |
Bacillota | UP of Clostridium kluyveri |
|
2.A.87.3.2 | Putative heptaprenyl diphosphate synthase component I of 173 aas and 5 TMSs. | Bacteria |
Bacillota | P-RFT family member of Clostridium leptum |
|
2.A.87.3.3 | Uncharacterized protein of 169 aas and 5 TMSs. | Bacteria |
Mycoplasmatota | UP of Acholeplasma laidlawii |
|
2.A.87.4.1 | Riboflavin uptake transporter of 228 aas and 5 TMSs (Gutiérrez-Preciado et al. 2015). | Bacteria |
Mycoplasmatota | RibV of Mesoplasma florum |
|
2.A.87.4.2 | Putative riboflavin transporter of 227 aas and 5 TMSs (Gutiérrez-Preciado et al. 2015). | Bacteria |
Mycoplasmatota | RibV of Mycoplasma capricolum |
|
2.A.87.4.3 | Uncharacterized protein, probably a riboflavin transporter of 234 aas and 5 TMSs. | Bacteria |
Mycoplasmatota | UP of Spiroplasma citri |
|
2.A.87.5.1 | Uncharacterized protein of 221 aas and 5 TMSs. | Archaea |
Candidatus Lokiarchaeota | UP of Candidatus Prometheoarchaeum syntrophicum |
|
2.A.87.5.2 | Uncharacterized protein of 238 aas and 5 TMSs in a 3 + 2 TMS arrangement. | Archaea |
Candidatus Heimdallarchaeota | UP of Candidatus Heimdallarchaeota archaeon (marine sediment metagenome) |
|
2.A.87.5.3 | Uncharaterized protein of 177 aas and 5 TMSs | Archaea |
DPANN group | UP of Candidatus Diapherotrites archaeon (marine metagenome) |
|
2.A.87.5.4 | Uncharacterized protein of 236 aas and 6 TMSs. | Archaea |
Euryarchaeota | UP of Pyrococcus furiosus |