2.A.88.8.6 YhhQ protein (DUF165) (encoded within the purine regulon (PurR) (Ravcheev et al., 2002)) (221 aas; 6 TMSs). It may be a 7-cyano-7-deazaguanine (preQ₀) transporter. PreQ0 is the product of the reaction catalyzed by GTP cyclhydrolase I, important for the synthesis of folic acid, and an intermediate of interest due to its central role in tRNA and DNA modification and secondary
metabolism (Zallot et al. 2017).
|
Accession Number: | B3WJF3 |
Protein Name: | Putative membrane protein |
Length: | 221 |
Molecular Weight: | 25303.00 |
Species: | Escherichia coli B171 [344601] |
Number of TMSs: | 6 |
Substrate |
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1: MNVFSQTQRY KALFWLSLFH LLVITSSNYL VQLPVSIFGF HTTWGAFSFP FIFLATDLTV
61: RIFGAPLARR IIFAVMIPAL LISYVISSLF YMGSWQGFGA LAHFNLFVAR IATASFMAYA
121: LGQILDVHVF NRLRQSRRWW LAPTASTLFG NVSDTLAFFF IAFWRSPDAF MAEHWMEIAL
181: VDYCFKVLIS IVFFLPMYGV LLNMLLKRLA DKSEINALQA S