2.A.9.1.3
Cytochrome c oxidase assembly protein 18, COX18 of 333 aas and 4 TMSs. Acts transiently as a membrane insertase within the subunit 2 module of Cytochrome oxidase (Bourens and Barrientos 2017). Plays a central role in the translocation
and export of the C-terminal part of the COX2 protein into the
mitochondrial intermembrane space (Gaisne and Bonnefoy 2006).
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| Accession Number: | Q8N8Q8 |
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| Protein Name: | Mitochondrial inner membrane protein COX18 |
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| Length: | 333 |
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| Molecular Weight: | 37063.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MLCRLGGRWL RPLPALQLWA RDLPLAPVPT SGAKRPTLPV WAVAPVSAVH ANGWYEALAA
61: SSPVRVAEEV LLGVHAATGL PWWGSILLST VALRGAVTLP LAAYQHYILA KVENLQPEIK
121: TIARHLNQEV AVRANQLGWS KRDARLTYLK NMRRLISELY VRDNCHPFKA TVLVWIQLPM
181: WIFMSFALRN LSTGAAHSEG FSVQEQLATG GILWFPDLTA PDSTWILPIS VGVINLLIVE
241: ICALQKIGMS RFQTYITYFV RAMSVLMIPI AATVPSSIVL YWLCSSFVGL SQNLLLRSPG
301: FRQLCRIPST KSDSETPYKD IFAAFNTKFI SRK