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2.A.95.1.1 MarC or YdeB of 221 aas and 6 TMSs. The role of MarC in MDR is controversial (McDermott et al., 2008). It may function in conjunction with YdeA, an MFS pump (TC# 2.A.1.2.15) (Zakataeva et al. 2006).
Accession Number:	P0AEY1
Protein Name:	Multiple antibiotic resistance protein MarC aka B1529
Length:	221
Molecular Weight:	23617.00
Species:	Escherichia coli [83333]
Number of TMSs:	6
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	antimicrobial agent

RefSeq:	AP_002150.1 NP_416046.1
Entrez Gene ID:	947132
Pfam:	PF01914
BioCyc:	EcoCyc:EG11637-MONOMER ECOL168927:B1529-MONOMER
KEGG:	ecj:JW1522 eco:b1529
Gene Ontology GO:0005887 C:integral to plasma membrane
References (7) [1] “Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli.” Cohen S.P.et.al. 8383113 [2] “A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.” Aiba H.et.al. 9097039 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis.” Drew D.et.al. 11867724 [6] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996 [7] “The marC gene of Escherichia coli is not involved in multiple antibiotic resistance.” McDermott P.F.et.al. 17954692

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FASTA formatted sequence

1:	MLDLFKAIGL GLVVLLPLAN PLTTVALFLG LAGNMNSAER NRQSLMASVY VFAIMMVAYY 
61:	AGQLVMDTFG ISIPGLRIAG GLIVAFIGFR MLFPQQKAID SPEAKSKSEE LEDEPSANIA 
121:	FVPLAMPSTA GPGTIAMIIS SASTVRQSST FADWVLMVAP PLIFFLVAVI LWGSLRSSGA 
181:	IMRLVGKGGI EAISRLMGFL LVCMGVQFII NGILEIIKTY H

2.A.95.1.1
MarC or YdeB of 221 aas and 6 TMSs. The role of MarC in MDR is controversial (McDermott et al., 2008). It may function in conjunction with YdeA, an MFS pump (TC# 2.A.1.2.15) (Zakataeva et al. 2006).

Cross database links:

Gene Ontology

References (7)

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2.A.95.1.1MarC or YdeB of 221 aas and 6 TMSs. The role of MarC in MDR is controversial (McDermott et al., 2008). It may function in conjunction with YdeA, an MFS pump (TC# 2.A.1.2.15) (Zakataeva et al. 2006).

Cross database links:

Gene Ontology

References (7)

External Searches:

Analyze:

2.A.95.1.1
MarC or YdeB of 221 aas and 6 TMSs. The role of MarC in MDR is controversial (McDermott et al., 2008). It may function in conjunction with YdeA, an MFS pump (TC# 2.A.1.2.15) (Zakataeva et al. 2006).