TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.1.22
The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins.

Accession Number:Q9X0T0
Protein Name:MalF1; aka Maltose ABC transporter, permease protein
Length:577
Molecular Weight:65769.00
Species:Thermotoga maritima [2336]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate alpha,alpha-trehalose, maltose, alpha-maltotriose, maltotetraose

Cross database links:

RefSeq: NP_229008.1   
Entrez Gene ID: 898281   
Pfam: PF00528   
BioCyc: TMAR243274:TM_1203-MONOMER   
KEGG: tma:TM1203   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006810 P:transport

References (1)

[1] “Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima.”  Nelson K.E.et.al.   10360571

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKNIVKLFLW FLLAILNIAL FWAGVFLFQN EYYELSIVLF SLLVLIDFFI INPRGYPYRY 
61:	TIPALILLFV LVLYPIYFTF KVAFTNYGTG HFMSRQEAIE RLLYDPNFSY VVDSTPVSYK 
121:	VFVVYDGLSP TDDFLILFKT GDTIFLGERP KPVVARGQEV LLSQFNLVPI TGETISLNGD 
181:	TFRIVPWPAD LSEINLVVRG EKTYKSFYSP DDEILRLNAP YFKSRIAQGY LVNAEYVLPD 
241:	GKKLALRIAP DGEWRFMYVE RLYRLAYKEI YDGVKMKITT TVVNNLTGRE VVEREGAFYD 
301:	VDENGNETFL VGFIDFVGWK NFLRIVKDPK VSGPFFRIFL WTFVWAVLSV VLSLAVGLPF 
361:	ALVLNNPRLK GRNLYRTLLI IPWAIPVFIS ALVWRNGLLN ESYGVINKFL LPLFGLEPIK 
421:	WFNDPFWARV GVLLVNVWLT FPYMMTISLG ALQSIPPELY EVAAIDGAGR FRRFVHITFP 
481:	LLMTIIAPLL VSSFAFSFNN FTIIYLITGG GPPIPNSTTP TGYTDILISY VYKLAFEGGQ 
541:	GQDFGFASAI SILIFFLVGG ISFVNFKLSG AFEEVSR