3.A.1.105.10 AbcG homologue, ABCH1 of 705 aas and 6 TMSs in a C-M arrangement. May be involved in steroid or drug efflux (Popovic et al. 2010). Of the vertbrates, it may be restricted to fish.
|
Accession Number: | F1QZ58 |
Protein Name: | Uncharacterized protein |
Length: | 705 |
Molecular Weight: | 78237.00 |
Species: | Danio rerio (Zebrafish) [7955] |
Number of TMSs: | 7 |
Substrate |
steroid, drug |
---|
1: SLESGTMKTD LEAGSFSAAI HCHDVCRSYG KLKVLNNLNL TLPQGQIYGL LGPSGCGKTT
61: LLKCIVGTLK ISRGHITVLG KPPAFPGHEV PGKMVGYMPQ DIALYNEFTI SNTLWFFGRI
121: HGLSSKETEA RMSFLIDFLD LPQKHSLVKN LSGGQRRRVS LGAALLQNPK LLILDEPTVG
181: VDPVLRAKIW QHLVEIVRGG QVSIIITTHY IEEARQANTV GLMRNGRLLA EGPPDAVMKQ
241: HNAATLETAF LQLCEDSDQS GPKQSPQGRL LDSSPSPDSM RDEIREPILR KSTSEDMPKC
301: KADWKVRARH IIPKWSNIAA LMIKTMVRMR RLPGSLCFQF LLPVIQICLM CLCIGGDPKN
361: IDVAVVNNES SPSAFSRSLL SFLDNTSINQ IGERFPFCFL QVSLSHSDAF DGIRNGEYWG
421: VIEFGENFTS YLTKRMLQPR VSREVVEGGS VHAWLDLTNR QIALMLQKKL HQAFEAFMEK
481: RLGSMSYMVA VPIKFEEPIY GSKNTDFTTF VTPGAVLSIT FYLAVGLTAL SFVLERKEGL
541: LDRCWVAGVS SLETMLAHLF SQLFVISVQI ILLLIFTLLV FNIPNEGSLA LVISLIVLQG
601: VTGISFGLVI SSAIDDEQSA NQAALGVFYP NLILSGVIWP VECIPYPLRY LSLVLPQTYA
661: SEALRCIMYR GWGLSRMMVW RGFAVTLGWN TFFLMLATII LKLRT