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| Accession Number: | P69874 |
| Protein Name: | Spermidine/putrescine import ATP-binding protein PotA aka B1126 |
| Length: | 378 |
| Molecular Weight: | 43028.00 |
| Species: | Escherichia coli [83333] |
| Location1 / Topology2 / Orientation3: | Cell inner membrane1 / Peripheral membrane protein2 |
| Substrate | spermidine, putrescine |
Cross database links:
| RefSeq: | AP_001752.1 NP_415644.1 |
|---|---|
| Entrez Gene ID: | 946323 |
| Pfam: | PF00005 PF08402 |
| BioCyc: | EcoCyc:POTA-MONOMER ECOL168927:B1126-MONOMER |
| KEGG: | ecj:JW1112 eco:b1126 |
Gene Ontology
GO:0043190
C:ATP-binding cassette (ABC) transporter complex
GO:0005886
C:plasma membrane
GO:0005524
F:ATP binding
GO:0015417
F:polyamine-transporting ATPase activity
GO:0005515
F:protein binding
GO:0015846
P:polyamine transport
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References (9)[1] “Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome.” Furuchi T.et.al. 1939142 [2] “A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.” Oshima T.et.al. 8905232 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Spermidine-preferential uptake system in Escherichia coli. ATP hydrolysis by PotA protein and its association with membranes.” Kashiwagi K.et.al. 7592703 [6] “Isolation of polyamine transport-deficient mutants of Escherichia coli and cloning of the genes for polyamine transport proteins.” Kashiwagi K.et.al. 2249996 [7] “Functions of potA and potD proteins in spermidine-preferential uptake system in Escherichia coli.” Kashiwagi K.et.al. 8366082 [8] “Transcriptional inhibition of the operon for the spermidine uptake system by the substrate-binding protein PotD.” Antognoni F.et.al. 9890949 [9] “The ATPase activity and the functional domain of PotA, a component of the spermidine-preferential uptake system in Escherichia coli.” Kashiwagi K.et.al. 11976340
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MGQSKKLNKQ PSSLSPLVQL AGIRKCFDGK EVIPQLDLTI NNGEFLTLLG PSGCGKTTVL 61: RLIAGLETVD SGRIMLDNED ITHVPAENRY VNTVFQSYAL FPHMTVFENV AFGLRMQKTP 121: AAEITPRVME ALRMVQLETF AQRKPHQLSG GQQQRVAIAR AVVNKPRLLL LDESLSALDY 181: KLRKQMQNEL KALQRKLGIT FVFVTHDQEE ALTMSDRIVV MRDGRIEQDG TPREIYEEPK 241: NLFVAGFIGE INMFNATVIE RLDEQRVRAN VEGRECNIYV NFAVEPGQKL HVLLRPEDLR 301: VEEINDDNHA EGLIGYVRER NYKGMTLESV VELENGKMVM VSEFFNEDDP DFDHSLDQKM 361: AINWVESWEV VLADEEHK