Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


3.A.1.12.3
Choline porter

Accession Number:Q45460
Protein Name:OPBA aka OpuBA aka PROV
Length:381
Molecular Weight:43075.00
Species:Bacillus subtilis [1423]
Location1 / Topology2 / Orientation3: Cell membrane1 / Lipid-anchor2
Substrate choline

Cross database links:

RefSeq: NP_391253.1   
Entrez Gene ID: 936230   
Pfam: PF00005    PF00571   
KEGG: bsu:BSU33730   

Gene Ontology

GO:0016020 C:membrane
GO:0015171 F:amino acid transmembrane transporter activity
GO:0005524 F:ATP binding
GO:0016887 F:ATPase activity
GO:0006865 P:amino acid transport
GO:0008152 P:metabolic process

References (3)

[1] “Characterization of a chimeric proU operon in a subtilin-producing mutant of Bacillus subtilis 168.”  Lin Y.et.al.   7592481
[2] “Two evolutionarily closely related ABC transporters mediate the uptake of choline for synthesis of the osmoprotectant glycine betaine in Bacillus subtilis.”  Kappes R.M.et.al.   10216873
[3] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MLTLENVSKT YKGGKKAVNN VNLKIAKGEF ICFIGPSGCG KTTTMKMINR LIEPSAGKIF 
61:	IDGENIMDQD PVELRRKIGY VIQQIGLFPH MTIQQNISLV PKLLKWPEQQ RKERARELLK 
121:	LVDMGPEYVD RYPHELSGGQ QQRIGVLRAL AAEPPLILMD EPFGALDPIT RDSLQEEFKK 
181:	LQKTLHKTIV FVTHDMDEAI KLADRIVILK AGEIVQVGTP DDILRNPADE FVEEFIGKER 
241:	LIQSSSPDVE RVDQIMNTQP VTITADKTLS EAIQLMRQER VDSLLVVNDE RVLQGYVDVE 
301:	IIDQCRKKAN LVSEVLHEDI YTVLGGTLLR DTVRKILKRG VKYVPVVDED RRLIGIVTRA 
361:	SLVDIVYDSL WGEEKQLAAL S