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3.A.1.134.11
Lantibiotic detoxification ABC transporter, VraD (252 aas)/VraE (626 aas; 10 TMSs)/VraH ( (Draper et al. 2015).  Upregulated in response to exposure to beta-defensin 3 (Sass et al. 2008).  Exports antimicrobial peptides such as nisin, bacitracin, daptomycin and gallidermin. Expression of vraH in the absence of vraDE is sufficient to mediate low-level resistance, but VraDEH is required to  confer high-level resistance against daptomycin and gallidermin. (Popella et al. 2016).

Accession Number:Q9RL74
Protein Name:ABC transporter
Length:252
Molecular Weight:27775.00
Species:Staphylococcus aureus [1280]
Substrate daptomycin, bacitracin, alphaprodine

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTILSVQHVS KTYGKKHTFQ ALKDINFDIQ KGEFVAIMGP SGSGKTTLLN VLSSIDQISS 
61:	GSVIANGQEL NKLNQKALAK FRKESLGFIF QDYSILPTLT VKENIMLPLS VQKMSKATME 
121:	ENYKAITTAL GIYDLGNKYP SELSGGQQQR TAAARAFVHK PQIIFADEPT GALDSKSAND 
181:	LLQRLEEMNK SFDTTIVMVT HDPVAASFAE RVIMLKDGQI HTQLYQEGRS KQAFYEDIVH 
241:	LQSVLGGVSN DI