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3.A.1.14.5
Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).

Accession Number:Q56992
Protein Name:HmuU aka YPO0280 aka Y0540
Length:334
Molecular Weight:35540.00
Species:Yersinia pestis [632]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate ferroheme b

Cross database links:

RefSeq: NP_667877.1    NP_991829.1    YP_002345362.1   
Entrez Gene ID: 1145487    1173126    2764130   
Pfam: PF01032   
BioCyc: YPES187410:Y0540-MONOMER    YPES214092:YPO0280-MONOMER    YPES229193:YP0435-MONOMER   
KEGG: ype:YPO0280    ypk:y0540    ypm:YP_0435   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005215 F:transporter activity
GO:0006826 P:iron ion transport

References (4)

[1] “The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem-protein complexes as iron sources.”  Hornung J.M.et.al.   9026634
[2] “Genome sequence of Yersinia pestis, the causative agent of plague.”  Parkhill J.et.al.   11586360
[3] “Genome sequence of Yersinia pestis KIM.”  Deng W.et.al.   12142430
[4] “Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.”  Song Y.et.al.   15368893
Structure:
4G1U     

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNGRVQPRLM LGFLLILLVI LALGSANMGA LSLSFRTLWN TSTNDAMWHI WLNIRLPRVL 
61:	LAVVVGCALA VSGTIMQGLF RNPLADPGLL GISSGAALCV GLIIVMPFSL PPLLALYSHM 
121:	VGAFIGSLAI STIIFTLSRW GHGNLARLLL AGIAINALCG AAVGVLTYIS DDQQLRQFSL 
181:	WSMGSLGQAQ WSTLLVASSL ILPTCILGLL QARQLNLLQL GDEEAHYLGV NVRQAKLRLL 
241:	LLSAILIGAA VAVSGVIGFI GLVVPHLIRM RIGADHRWLL PGAALGGACL LLTADTLART 
301:	LVAPAEMPVG LLTSLLGGPY FLWLILRQRE QRSG