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3.A.1.14.5 Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).
Accession Number:	Q56993
Protein Name:	HmuV aka YPO0279 aka Y0539
Length:	266
Molecular Weight:	29658.00
Species:	Yersinia pestis [632]
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Peripheral membrane protein²
Substrate	ferroheme b

Structure:
RefSeq:	NP_991828.1 YP_002345361.1
Entrez Gene ID:	1173125 2764129
Pfam:	PF00005
BioCyc:	YPES187410:Y0539-MONOMER YPES214092:YPO0279-MONOMER YPES229193:YP0434-MONOMER
KEGG:	ype:YPO0279 ypk:y0539 ypm:YP_0434
Gene Ontology GO:0005886 C:plasma membrane GO:0005524 F:ATP binding GO:0015439 F:heme-transporting ATPase activity GO:0015886 P:heme transport
References (4) [1] “Molecular characterization of the hemin uptake locus (hmu) from Yersinia pestis and analysis of hmu mutants for hemin and hemoprotein utilization.” Thompson J.M.et.al. 10417152 [2] “Genome sequence of Yersinia pestis, the causative agent of plague.” Parkhill J.et.al. 11586360 [3] “Genome sequence of Yersinia pestis KIM.” Deng W.et.al. 12142430 [4] “Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans.” Song Y.et.al. 15368893
4G1U

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MVDMAVTPVA LLEASHLHYH VQQQALINDV SLHIASGEMV AIIGPNGAGK STLLRLLTGY 
61:	LSPSHGECHL LGQNLNSWQP KALARTRAVM RQYSELAFPF SVSEVIQMGR APYGGSQDRQ 
121:	ALQQVMAQTD CLALAQRDYR VLSGGEQQRV QLARVLAQLW QPQPTPRWLF LDEPTSALDL 
181:	YHQQHTLRLL RQLTRQEPLA VCCVLHDLNL AALYADRIML LAQGKLVACG TPEEVLNAET 
241:	LTQWYQADLG VSRHPESALP QIYLRQ

3.A.1.14.5
Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

3.A.1.14.5Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).

Cross database links:

Gene Ontology

References (4)

External Searches:

Analyze:

3.A.1.14.5
Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle (Mattle et al., 2010).