3.A.1.2.17
General nucleoside uptake porter, NupABC/BmpA (transports all common nucleosides as well as 5-fluorocytidine, inosine, deoxyuridine and xanthosine) (Martinussen et al., 2010) (Most similar to 3.A.1.2.12). NupA is 506aas with two ABC (C) domains. NupB has 8 predicted TMSs, NupC has 9 or 10 predicted TMSs in a 4 + 1 (or 2) + 4 arrangement.
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| Accession Number: | A2RKA7 |
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| Protein Name: | Purine/cytidine ABC transporter ATP-binding protein |
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| Length: | 506 |
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| Molecular Weight: | 55544.00 |
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| Species: | Lactococcus lactis subsp. cremoris (strain MG1363) [416870] |
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| Substrate |
nucleoside |
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| Entrez Gene ID: |
4797583
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| Pfam: |
PF00005
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| KEGG: |
llm:llmg_1123
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[1] “The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363.” Wegmann U. et.al. 17307855
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1: MANETVIQMI DVTKRFGDFV ANDKVNLELK KGEIHALLGE NGAGKSTLMN ILSGLLEPSE
61: GEVHVKGKLE NIDSPSKAAN LGIGMVHQHF MLVDAFTVTE NIILGNEVTK GINLDLKTAK
121: KKILELSERY GLSVEPDALI RDISVGQQQR VEILKTLYRG ADILIFDEPT AVLTPAEITE
181: LMQIMKNLIK EGKSIILITH KLDEIRAVAD RITVIRRGKS IDTVELGDKT NQELAELMVG
241: RSVSFITEKA AAQPKDVVLE IKDLNIKESR GSLKVKGLSL DVRAGEIVGV AGIDGNGQTE
301: LVKAITGLTK VDSGSIKLHN KDITNQRPRK ITEQSVGHVP EDRHRDGLVL EMTVAENIAL
361: QTYYKPPMSK YGFLDYNKIN SHARELMEEF DVRGAGEWVS ASSLSGGNQQ KAIIAREIDR
421: NPDLLIVSQP TRGLDVGAIE YIHKRLIQAR DEGKAVLVIS FELDEILNVS DRIAVIHDGQ
481: IQGIVSPETT TKQELGILMV GGNINE