3.A.1.201.40
Serine protease/ABC transporter B family protein TagA of 1752 aas and 9 putative TMSs with one N-terminal TMS followed by a large hydrophilic region that may correspond to the protease domain, followed by 8 putative TMSs in a 2 + 2 + 2 + 2 TMS arrangement and the ATPase domain. It is required for general cell fate determination at
the onset of development andis required for the specification of an initial
population of prespore cells in which tagA is expressed. It is also required for
normal SDF-2 signaling during spore encapsulation (Good et al. 2003; Cabral et al. 2006).
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| Accession Number: | Q9GTN7 |
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| Protein Name: | Serine protease/ABC transporter B family protein tagA |
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| Length: | 1752 |
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| Molecular Weight: | 192812.00 |
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| Species: | Dictyostelium discoideum (Slime mold) [44689] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MNKKLFIFGL SLFLFLFIFN LSLSLKLSSK NNFYNHNHIN NQIHRNNEGN NKLSKLIHLH
61: NDVIDTTISN RDNILFNKKS LNQKSKGSLF LVHLNGPIEK QVHNELIKQL DQLFNGGEII
121: HYIPDNTYLI SMIGSDNNDN NNNNKIELIN RLKELIPSIQ WLKPLEPRLK ISPLFKQNQF
181: QGDNQNEIDQ LRIYYHENSN QQSNDIDNII SESSLTLVEK ELISNNNNNN NNVLITVNLK
241: NSKLSLESII YKISTRSLVY WIEPSSSKLI KHTPSNKFAH YSIQSGSAST TSTPIWDVIG
301: IKGDGEIVGC ADTGIDINHC FFYDTNPIGS THRKIISYSS GNGDQIDEID GHGTHIVGTI
361: IGSTTVDPSV SEFSGGAPNS KVAFVDLQVG SGNGLSIQSN LTAIYQSTYD QNAKVHCDAW
421: NSNIGPFYTG VTEMIDRFQW DHPDFLVVRS AGNNVNFGFN SIYTLSQEST SKNSLVVGSS
481: NQPSSTYLSS IDYWDWDFIY NSIRTSVCTQ GQSIYGITCS DVPTQTTSVD IQTQCCSNPI
541: LAKICCSTEI QQQYQTNSTV YSEFIPSLFS GVGPTSDGRL KPDLLAPGSP IISSRSLGPS
601: STINHCSPIT SGIATSALIA MEGSSQAAAV ATSAAVLVRQ YYRDGYFING KVNSSVGFQP
661: SASLVKATLI NTASINVDST LEYSQGFGNI QLSKLITTTN AQTTSLDIPS SIEKADPIIN
721: TGETNSYCFS LDSKADIDIT LVWTDPAGSP LSTFTLVNNL DLALLAFVDG ELSIYSGNSE
781: TIFKNTSQVI FDQLNNVEVI RIKDAPIGSY DVKIFGTNIV IPNQSYSVVI RTSGGTTLMK
841: ESECAQCFYD PNDDQSQMCE FDNGIGTQYC KDDNRFSKCV VYECNTGYVF DNGITKSCVT
901: TLALTLYDIV LLGIFGIIIV GAVIFVLVCY KSKSLDQNKY FSLSKDKGGD GNSIRSNSVA
961: GNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNSNGKQS NIELNSVGGG DDGTPNGDDQ
1021: QQQNNSPQYD EDGRLISGQE VEISIFEVIS LGKPESKILG LALFLSFIDV ALGLAVPLVA
1081: ANIFDYLYAG ETGKISTTIL TFALIIIGMI IVQFLSGILL ALAGHRIIAR LRREMFASLL
1141: KQDMAFFNER KTGELMSRLA SDVSSVRSII SDSIPHMIIQ IATIGGTLIM LFIISWKLSL
1201: VVLCPLPILL VFSKFYGGYI EVISVKVQDA LADAATHAAE TLFNMKTVRW FSAEEREVAK
1261: FSKLISVSYK IALKMTIWNG IYSSTSGIFE QLSVFILLWY GSSLVSNGDL TPSMLIAFNL
1321: FLPFITGAVT QVASLYTTYK SYKGSSYRFF EIMQRVPDIQ GEGGITRTKV RGDIQFNKVS
1381: FAYSSNPDQL VLEKIDIKFE PGTITALIGP SGGGKSTMLS LIGRLYNIDG GSITLDGTNI
1441: KDFNVPNLHE HISIVNQEPS LFSGSIAENI MFGKPTATRS EIIEACKQAN AHDFITAMPE
1501: GYDTLIGERG TALSGGQKQR IAIARTIIKN PTVLLLDETT SELDVESEKL VQDSIDKLVV
1561: GRTVIIVAHR LTTILTADII AVVSDSTISE MGTPEELLAK KGMFYDFVQI QYGKQGEELD
1621: IQLPSNSRNT RNADKLRNRS ETIKQIAKIN NIIPIHRPQR GDDDNEDDEN NSGQGSSRSP
1681: PPMWRQAKKN ANVNKSMLLT RRNTHVQHQS SSGGWQKGNV DDKLQRVLQK SRKKGFMNNQ
1741: DHKDIKATLV LY