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|---|---|
| Accession Number: | Q9ZR72 |
| Protein Name: | Pgp1 aka AtPgp1 |
| Length: | 1286 |
| Molecular Weight: | 140573.00 |
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | cycloheximide, auxin, drug |
Cross database links:
| RefSeq: | NP_181228.1 |
|---|---|
| Entrez Gene ID: | 818265 |
| Pfam: | PF00664 PF00005 |
| KEGG: | ath:AT2G36910 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0010329
F:auxin efflux transmembrane transporter acti...
GO:0005515
F:protein binding
GO:0043481
P:anthocyanin accumulation in tissues in resp...
GO:0009734
P:auxin mediated signaling pathway
GO:0009926
P:auxin polar transport
GO:0009640
P:photomorphogenesis
GO:0009958
P:positive gravitropism
GO:0008361
P:regulation of cell size
GO:0009637
P:response to blue light
GO:0009624
P:response to nematode
GO:0048443
P:stamen development
GO:0055085
P:transmembrane transport
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References (14)[1] “Structure of an mdr-like gene from Arabidopsis thaliana: evolutionary implications.” Dudler R.et.al. 1372894 [2] “Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.” Lin X.et.al. 10617197 [3] “Empirical analysis of transcriptional activity in the Arabidopsis genome.” Yamada K.et.al. 14593172 [4] “Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxin-mediated development.” Noh B.et.al. 11701880 [5] “Involvement of an ABC transporter in a developmental pathway regulating hypocotyl cell elongation in the light.” Sidler M.et.al. 9761790 [6] “A role for ectophosphatase in xenobiotic resistance.” Thomas C.et.al. 10760241 [7] “The Arabidopsis thaliana ABC protein superfamily, a complete inventory.” Sanchez-Fernandez R.et.al. 11346655 [8] “TWISTED DWARF1, a unique plasma membrane-anchored immunophilin-like protein, interacts with Arabidopsis multidrug resistance-like transporters AtPGP1 and AtPGP19.” Geisler M.et.al. 14517332 [9] “Multiherbicide tolerance conferred by AtPgp1 and apyrase overexpression in Arabidopsis thaliana.” Windsor B.et.al. 12640467 [10] “Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database.” Nuehse T.S.et.al. 15308754 [11] “Two homologous ATP-binding cassette transporter proteins, AtMDR1 and AtPGP1, regulate Arabidopsis photomorphogenesis and root development by mediating polar auxin transport.” Lin R.et.al. 15908594 [12] “Cellular efflux of auxin catalyzed by the Arabidopsis MDR/PGP transporter AtPGP1.” Geisler M.et.al. 16212599 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MDNDGGAPPP PPTLVVEEPK KAEIRGVAFK ELFRFADGLD YVLMGIGSVG AFVHGCSLPL 61: FLRFFADLVN SFGSNSNNVE KMMEEVLKYA LYFLVVGAAI WASSWAEISC WMWSGERQTT 121: KMRIKYLEAA LNQDIQFFDT EVRTSDVVFA INTDAVMVQD AISEKLGNFI HYMATFVSGF 181: IVGFTAVWQL ALVTLAVVPL IAVIGGIHTT TLSKLSNKSQ ESLSQAGNIV EQTVVQIRVV 241: MAFVGESRAS QAYSSALKIA QKLGYKTGLA KGMGLGATYF VVFCCYALLL WYGGYLVRHH 301: LTNGGLAIAT MFAVMIGGLA LGQSAPSMAA FAKAKVAAAK IFRIIDHKPT IERNSESGVE 361: LDSVTGLVEL KNVDFSYPSR PDVKILNNFC LSVPAGKTIA LVGSSGSGKS TVVSLIERFY 421: DPNSGQVLLD GQDLKTLKLR WLRQQIGLVS QEPALFATSI KENILLGRPD ADQVEIEEAA 481: RVANAHSFII KLPDGFDTQV GERGLQLSGG QKQRIAIARA MLKNPAILLL DEATSALDSE 541: SEKLVQEALD RFMIGRTTLI IAHRLSTIRK ADLVAVLQQG SVSEIGTHDE LFSKGENGVY 601: AKLIKMQEAA HETAMSNARK SSARPSSARN SVSSPIMTRN SSYGRSPYSR RLSDFSTSDF 661: SLSIDASSYP NYRNEKLAFK DQANSFWRLA KMNSPEWKYA LLGSVGSVIC GSLSAFFAYV 721: LSAVLSVYYN PDHEYMIKQI DKYCYLLIGL SSAALVFNTL QHSFWDIVGE NLTKRVREKM 781: LSAVLKNEMA WFDQEENESA RIAARLALDA NNVRSAIGDR ISVIVQNTAL MLVACTAGFV 841: LQWRLALVLV AVFPVVVAAT VLQKMFMTGF SGDLEAAHAK GTQLAGEAIA NVRTVAAFNS 901: EAKIVRLYTA NLEPPLKRCF WKGQIAGSGY GVAQFCLYAS YALGLWYASW LVKHGISDFS 961: KTIRVFMVLM VSANGAAETL TLAPDFIKGG QAMRSVFELL DRKTEIEPDD PDTTPVPDRL 1021: RGEVELKHID FSYPSRPDIQ IFRDLSLRAR AGKTLALVGP SGCGKSSVIS LIQRFYEPSS 1081: GRVMIDGKDI RKYNLKAIRK HIAIVPQEPC LFGTTIYENI AYGHECATEA EIIQAATLAS 1141: AHKFISALPE GYKTYVGERG VQLSGGQKQR IAIARALVRK AEIMLLDEAT SALDAESERS 1201: VQEALDQACS GRTSIVVAHR LSTIRNAHVI AVIDDGKVAE QGSHSHLLKN HPDGIYARMI 1261: QLQRFTHTQV IGMTSGSSSR VKEDDA