3.A.1.204.19
ABC transporter G family member 3, ABCG3; ABCG.3. Also called the white-brown complex homologue protein 3, WBC3, of 730 aas. It is a homologue of animal eye pigment precursor uptake porters. The white, scarlet (TC# 3.A.1.204.17), and brown (3.A.1.204.18) genes of Drosophila melanogaster encode
ABC transporter proteins involved with the uptake and storage of metabolic
precursors to the red and brown eye colour pigments (Mackenzie et al. 2000). It may also transport sesquiterpenes, defensive agents or pheromones.
(Lefèvre and Boutry 2018). Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters (PakuĊa et al. 2023). See also, Salgado et al. 2023.
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| Accession Number: | Q9ZUU9 |
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| Protein Name: | ABC transporter G family member 3 |
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| Length: | 730 |
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| Molecular Weight: | 81039.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 8 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MEEIQSQSDL YRSSSSSASS PTSRVPSSHF FYVRKPGSLR QPISFEDSPE WEDTPDVDLR
61: MEDEAGGGDS INDATTTPVS PSLSKMNSGS MASPPVPEGG AGTGVVRKIA GASIAWKDLT
121: VTMKGKRKYS DKVVKSSNGY AFPGTMTVIM GPAKSGKSTL LRALAGRLPP SAKMYGEVFV
181: NGSKSHMPYG SYGFVERETQ LIGSLTVREF LYYSALLQLP GFLFQKRSVV EDAIQAMSLS
241: DYANKLIGGH CYMKGLRSGE RRRVSIAREL VMRPHILFID EPLYHLDSVS ALLMMVTLKK
301: LASMGCTLVF TIYQSSTEVF GLFDRICLLS NGNTLFFGET LACLQHFSNA GFPCPIMQSP
361: SDHFLRAINT DFDRIIAMCK NWQDDNGDFS AVNMDTAVAI RTLEATYKSS ADADSVEAMI
421: IKLTEREGTQ LKSKGKAGAA TRVAVLTWRS LLVMSREWKY YWLRLILYMI LTLSIGTLYS
481: GLGHSLSSVA TRVAAVFVFV SFASLLGIAG IPSLLKEIKI YRSEASNQHS GAFVFLLGQF
541: LGSIPFLFLM SISSSLVFYF MVGLRDDFSL LMYFVLNFFM CLLVNEGLML FIACIWRDVY
601: WSTLTLISVH VIMMLAAGHF RIRTALPKPV WTYPFAYISF HTYSIEGLLE NEYLGEVFAV
661: GEVRSISGYQ AIQGNYQISP DTNAKWRNML VLLAMAFGYR LLVYVLLRFG LNKNVSGRLL
721: LSHKKNNSSR